| 小儿急性阑尾炎细菌移位与阑尾组织NOS、血清NO及IL-10的关系 |
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| 引用本文： | 张兆杰,王瑞英,马晓峰.小儿急性阑尾炎细菌移位与阑尾组织NOS、血清NO及IL-10的关系[J].中国现代医生,2013,51(12):39-40. |
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| 作者姓名： | 张兆杰 王瑞英 马晓峰 |
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| 作者单位： | 1. 山东省潍坊市妇幼保健院小儿外科,山东潍坊,261011
2. 山东省潍坊市妇幼保健院内科,山东潍坊,261011 |
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| 摘 要： | 目的 探讨小儿急性阑尾炎发生细菌移位情况,分析其与阑尾组织中的NOS、血清中NO及IL-10的关系.方法选择在我院进行治疗的急性阑尾炎患儿24例为阑尾炎组,分别于术前和术后7 d采集静脉血,术中吸取腹腔液体.选择肠旋转不良且无阑尾炎的患儿15例为肠旋转不良组,选择20例健康儿童为正常对照组,采集血标本.检测全血细菌DNA,收集的腹腔液体和切取的淋巴结进行细菌培养,测定阑尾组织NOS的表达情况,检测血清中NO和IL-10的水平.结果 NO与NOS呈负相关,与IL-10成正相关.结论 小儿化脓性阑尾炎可出现肠道细菌移位与NO有密切关系.
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| 关 键 词： | 小儿急性阑尾炎 细菌移位 一氧化氮合成酶 一氧化氮 |
Relationship between bacterial translocation in children acute appendicitis and appendix NOS,serum NO,IL-10 |
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| Authors: | ZHANG Zhaojie WANG Ruiying MA Xiaofeng |
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| Institution: | 1.Department of Pediatric Surgery,Weifang Maternal and Child Heahh Hospital in Shandong Province,Weifang 261011, China; 2.Department of Internal Medicine, Weifang Maternal and Child Health Hospital in Shandong Province, Weifang 261011 ,China |
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| Abstract: | Objective To discuss relationship between bacterial translocation in children acute appendicitis and ap- pendix NOS, serum NO, IL-10. Methods Selected 24 cases with children acute appendicitis, were collected phlebo- blood before operation and 7d after operation. Peritoneal fluid were collected during operation. 15 cases with malmta- tion of intestines and without acute appendicitis were selected, and 20 cases health children. Bacterial DNA were de- tected, and collection of peritoneal fluid and chipped lymph nodes for bacterial culture. NOS was detected. Results NO showed negative correlation with NOS, and showed positive correlation with IL-10. Conclusion Bacterial translo- cation in children acute appendicitis has a close relation with NO. |
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| Keywords: | Children acute appendicitis Bacterial translocation NOS NO |
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