| 99mTc—DTPA肾动态显像与胱抑素C对糖尿病肾病的诊断价值 |
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| 引用本文： | 施良,李龙,陈军建,周建明.99mTc—DTPA肾动态显像与胱抑素C对糖尿病肾病的诊断价值[J].中国实验诊断学,2010,14(3):410-412. |
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| 作者姓名： | 施良 李龙 陈军建 周建明 |
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| 作者单位： | 1. 江苏大学附属医院,内分泌科,江苏,镇江212001
2. 江苏大学附属医院,核医学科,江苏,镇江212001 |
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| 基金项目： | 江苏大学2008年度临床医学科技发展基金资助 |
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| 摘 要： | 目的探讨血清胱抑素C检测与蚰99mTc-DTPA肾动态显像在早期糖尿病肾病中的诊断价值。方法按尿白蛋白排泄率将我院收治的己确诊2型糖尿病患者96例分为3组：糖尿病正常白蛋白尿组、微量白蛋白尿组、大量白蛋白尿组，采用示踪99mTc-DTPA二乙胺五乙酸（99mTc-DTPA）检测肾小球滤过率，同时测定血清胱抑索C，血肌酐及糖化血红蛋白，并设立正常对照组27例。采用统计方法分析结果。结果99mTc-DTPA GFR在尿白蛋白正常组明显高于微量、大量白蛋白尿组和对照组（P〈0．05）；血清胱抑素C在微量及大量白蛋白尿组明显高于对照组及尿白蛋白正常的糖尿病组（P〈0．05）；血清胱抑素C与99mTc-DTPA GFR呈负相关（P〈0．05）。结论‰Te—DTPAGFR及血清胱抑素C检测能更早的判断糖尿病肾脏损害程度，为糖尿病肾病临床分期提供依据。
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| 关 键 词： | 胱抑素c 糖尿病肾病 肾小球率过滤 99mTc-DTPA二乙胺五乙酸 肾动态显像 |
The meaning of ~(99m)Tc-DTPA renal dynamic imaging with cystatin C in diabetic nephropathy diagnosis |
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| SHI Liang,LI Long,CHEN Jun-jian,et al..The meaning of ~(99m)Tc-DTPA renal dynamic imaging with cystatin C in diabetic nephropathy diagnosis[J].Chinese Journal of Laboratory Diagnosis,2010,14(3):410-412. |
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| Authors: | SHI Liang LI Long CHEN Jun-jian |
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| Institution: | SHI Liang,LI Long,CHEN Jun-jian,et al.(The Affiliated Hospital of Jiangsu University,Zhenjiang 212001,China) |
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| Abstract: | Objective To probe into the clinical significance of isotope 99m Tc-DTPA renal dynamic imaging and serum cystatin C(ScysC) in early diabetic nephropathy(DN).Methods The study was performed on 96 type 2 diabetic patients from Affiliated Hospital of Jiangsu University.The patients were classified into three groups according to urine albumin excretion rate(UAER) as follows: the normal albuminuric,microalbuminuric and macroalbuminuric group.And other 27 healthy subjects were recruited as control group.ScysC,ser... |
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| Keywords: | cystatin C diabetic nephropathy GFR 99mTC-DTPA renal dynamic imaging |
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