| PTTG 在垂体腺瘤各亚型中的表达与分析 |
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| 引用本文： | 吕中华,张学新,张锐,王洪滨. PTTG 在垂体腺瘤各亚型中的表达与分析[J]. 现代肿瘤医学, 2012, 20(10): 2037-2039 |
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| 作者姓名： | 吕中华 张学新 张锐 王洪滨 |
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| 作者单位： | 哈尔滨医科大学附属第三医院神经外科,黑龙江 哈尔滨,150040 |
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| 摘 要： | 目的:研究PTTG与垂体瘤的各亚型的相关性.方法:用免疫组化方法检测92例垂体肿瘤病人PTTG.其中29例GH,20例PRL,10例ACTH,11例FSH/LH,9例TSH和13例无功能腺瘤.结果:PTTG在细胞质内显著表达,各亚型中GH型是表达最高,PRL腺瘤表达最低,各亚型的阳性表达率与PRL亚型阳性表达率对比均有统计学意义.结论:重体腺瘤不同垂体亚型中PTTG的表达阳性率及表达强度不同,PTTG检测,可为早期诊断垂体腺瘤( GH、PRL、ACTH、FSH/LH、TSH)亚型和无功能型提供参考.
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| 关 键 词： | PTTG 垂体腺瘤 亚型 免疫组织化学 |
Expression of PTTG in pituitary adenoma |
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| LV Zhonghua , ZHANG Xuexin , ZHANG Rui , WANG Hongbin. Expression of PTTG in pituitary adenoma[J]. Journal of Modern Oncology, 2012, 20(10): 2037-2039 |
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| Authors: | LV Zhonghua ZHANG Xuexin ZHANG Rui WANG Hongbin |
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| Affiliation: | Department of Neurosurgery,Third Affiliated Hospital of Harbin Medical University,Heilongjiang Harbin 150040,China. |
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| Abstract: | Objective:To study the relation between PTTG and pituitary tumor subtypes.Methods: Immunohistochemical teswas used to detect the expression of PTTG in 92 cases of pituitary cancer patients.Results: PTTG was high expressed in the cytoplasm.Subtypes of GH-type was the highest expression,PRL adenoma was the lowest.Conclusion: In different subtypes of pituitary tamor PTTG expression was different. |
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| Keywords: | PTTG pituitary adenoma subtype immunohistochemistry |
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