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Maternal serum Netrin-1 levels as a new biomarker of preeclampsia |
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| Authors: | Yasemin Çekmez Şebnem Garip İpek Ulu Serdar Gülşen Esra Tuştaş Haberal Yusuf Olgac |
| Affiliation: | 1. Department of Obstetrics and Gyneacology, Health Sciences University Umraniye Medical and Research Hospital, ?stanbul, Turkey, yaseminkandicekmez@hotmail.com;3. Department of Biochemistry, Kemerburgaz Un?versity, ?stanbul, Turkey, and;4. Department of Obstetrics and Gyneacology, Health Sciences University Umraniye Medical and Research Hospital, ?stanbul, Turkey,;5. Department of Obstetrics and Gyneacology, Florence Nightingale Hospital, ?stanbul, Turkey |
| Abstract: | Aim: The aim of this study was to investigate whether the Netrin-1 levels in maternal serum was associated with the presence of preeclampsia (PE).Methods: Total 72 patients, including 28 normal pregnant women and 44 patients with PE, were included in this study. Maternal serum Netrin-1 concentration was measured by enzyme-linked immunosorbent assay (ELISA).Results: Maternal serum Netrin-1 levels were detected statistically higher in preeclamptic group than control group (p?p?>?0.05).Conclusion: Maternal serum Netrin-1 has a potential to be a new marker for the detection of PE. |
| Keywords: | Netrin-1 placenta preeclampsia vasculogenesis |