| 负荷剂量阿托伐他汀对PCI相关心肌梗死发生率的影响 |
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| 引用本文： | 温连彬,秦亚录,范忠才.负荷剂量阿托伐他汀对PCI相关心肌梗死发生率的影响[J].临床医学工程,2013,20(1):29-31. |
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| 作者姓名： | 温连彬 秦亚录 范忠才 |
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| 作者单位： | 泸州医学院附属医院ICU;郫县人民医院;泸州医学院附属医院,心内科 |
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| 摘 要： | 目的探讨术前24h给予负荷剂量阿托伐他汀(80mg)对围术期心肌保护作用。方法选择56例诊断明确并行PCI治疗的不稳定型心绞痛患者,随机分为阿托伐他汀组28例(常规治疗加PCI术前24小时内给予阿托伐他汀80mg)和对照组28例(常规治疗)。所有患者均于术后24小时抽取静脉血,检测血浆肌酸激酶同工酶(CK-MBmass)、肌钙蛋白(cTnTmass)。结果 PCI术后24h两组患者CK-MB、cTnT水平均较术前明显升高,术前术后比较差异有统计学意义;对照组术后CK-MB升高>3倍正常上限发生率明显高于阿托伐他汀组(28.6%vs.7.1%,P=0.036),cTnT升高>3倍正常上限发生率亦明显高于阿托伐他汀组(35.7%vs10.7%,P=0.028),差异有统计学意义。结论术前24小时给予负荷剂量阿托伐他汀(80mg)可显著降低PCI相关心肌梗死发生率。
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| 关 键 词： | PCI相关心肌梗死 不稳定型心绞痛 阿托伐他汀 经皮冠状动脉介入治疗 |
Impact of a Single High Loading Dose of Atorvastatin before Percutaneous Coronary Intervention on Incidence of PCI-Related Myocardial Infarction |
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| WEN Lianbin,QIN Yalu,FAN Zhongcai.Impact of a Single High Loading Dose of Atorvastatin before Percutaneous Coronary Intervention on Incidence of PCI-Related Myocardial Infarction[J].Medical and Health Care Instruments,2013,20(1):29-31. |
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| Authors: | WEN Lianbin QIN Yalu FAN Zhongcai |
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| Institution: | 1 ICU,the Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China;2 Pixian People’s Hospital,Chengdu 611700,China;3 Department of Cardiology,the Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China; |
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| 本文献已被 CNKI 等数据库收录！ |
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