萎缩性阴道炎阴道菌群的研究

目的：研究萎缩性阴道炎患者的阴道菌群分布情况。方法：收集萎缩性阴道炎病人５０ 例、绝经前健康妇女３０ 例和绝经后阴道萎缩妇女２０ 例，进行阴道需氧菌和厌氧菌培养。结果：５０ 例萎缩性阴道炎组共分离出需氧菌６５ 株，分离率由高到低前４ 位依次是大肠埃希氏菌（１３／５０ ，２６ ％ ） 、表皮葡萄球菌（９／５０ ，１８ ％ ） 、粪链球菌（７／５０ ，１４ ％ ） 和绿色链球菌（６／５０ ，１２ ％ ） ，分离出厌氧菌５６ 株，分离率由高到低前４ 位依次是拟杆菌（２１／５０ ，４２ ％ ） 、消化链球菌（１９／５０ ，３８ ％ ） 和真杆菌（６／５０ ，１２ ％ ） 。除大肠埃希氏菌的分离率明显高于绝经前对照组外，其余各菌群与另外两组比较无明显差异， Ｐ ≤００５ 。结论：萎缩性阴道炎的菌群分布除大肠埃希氏菌外，其它菌群与绝经前妇女基本相似。

A Study of Vaginal Microflora in Atrophic Vaginitis

Objective : To study the vaginal microflora in atrophic vaginitis patients , postmenopausal women andpre menopausal women . Methods : Fifty postmenopausal patients with atrophic vaginitis , 20 postmenopausal women ofvaginal atrophy without any signs of vaginitis and 30 pre menopausal healthy women were enrolled in the study . Results : The vaginal p Hvalue of atrophic vaginitis patients was significantly higher than the p Hvalue of pre menopausal women . In atrophic vaginitis group ,there were totally 65 strains of aerobic bacteria and 56 strains of anaerobic bacteria isolated . The isolation rates of aerobic bacteria were 26 % ,18 % ,14 % and 12 % in escherichia coli ,staphylococcus epidermidis ,enterococcus and green streptococcus respectively . Theisolation rates of anaerobic bacteria were 42 % ,38 % and 12 % inbacteroides ,peptostreptococcus and eubacterium respectively . The escherichia coli was more com monin atrophic vaginitisgroup than in pre menopausal healthy group . There were no significantly differences about other bacteria among the threegroups. Conclusion : The resultindicated thatthe aerobic (except escherichia coli) and anaerobic bacteria isolated fromthe culturesin atrophic vaginitis patients were similar with the vaginal microflora of pre menopausal women . These bacte ria might be conditional pathogen in postmenopausal patients .