广州地区部分企业职工乙肝病毒感染标志物调查分析

目的了解广州地区部分企业职工乙肝病毒感染情况.方法对2001～2003年在我院作健康体检的广州地区部分企业职工的乙肝"两对半"体检资料进行分析.结果调查3117例(男1860,女1257)企业职工,全部静脉抽血作乙肝病毒感染标志物"两对半"(HBsAg、HBsAb、HBeAg、HBeAb、HBcAb 5项)检查,其中HBsAg和HBsAb均阴性606人(19.44%),HBsAb阳性2 047人(65.67%),HBsAg阳性464人(14.89%).而HBsAg和HBsAb阴性的606人中HBeAb或HBcAb阳性,或两者同时阳性56人(1.80%).结论本调查职工HBsAg阳性率为14.89%,高于全国平均水平;HBsAb阳性率为65.67%;HBsAg和HBsAb均为阴性占19.44%,易感者比率较高,有必要及早采取注射乙肝疫苗等有效干预措施,降低受感染的危险性,减少乙型肝炎、肝硬化及肝癌的发病率.

The investigation on hepatitis B virus markers among some workers in Guangzhou region

Objective To investigate infection status of hepatitis B virus among some enterprises workers in Guangzhou region. Methods A cross-sectional investigation on hepatitis B virus markers was conducted in four factories workers from 2001 to 2003. Results 3 117 worker's serum was tested for HBsAg, HBsAb, HBeAg, HBeAb and HBcAb.The result shows:606 cases were negative both in HBsAg and in HBsAb(19.44%). 2 047 cases were positive in HBsAb(65.67%). 464 cases were positive in HBsAg(14.89%). Among 606 negative cases both in HBsAg and in HbsAb, 56 cases were only positive in HBeAb or HBcAb and in the both(1.80%). Conclusion HBsAg positive rate was higher in our study than national average level. The susceptible rate was higher in G.Z. region(the negative rates both in HBsAg and in HBsAb were 19.44%). It is necessary to vaccinate hepatitis B virus earlier to prevent from infection of hepatitis B, liver cirrhosis and hepatocellular carcinoma.