| 阿米替林增强左旋四氢巴马汀的镇痛作用 |
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| 引用本文： | 陈屏,陈佩珍,袁跃萍. 阿米替林增强左旋四氢巴马汀的镇痛作用[J]. 药学与临床研究, 2003, 11(5): 66-68 |
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| 作者姓名： | 陈屏 陈佩珍 袁跃萍 |
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| 作者单位： | 江南大学医学系,无锡,214063 |
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| 摘 要： | 目的 探讨阿米替林增强左旋四氢巴马汀 (L THP)的镇痛作用。方法 采用热板法和化学剌激法进行镇痛实验。结果阿米替林两组剂量 (4 2mg/kg ,8 3mg/kg)均加强了L THP的镇痛作用 ,镇痛作用时间持续 4h。结论 阿米替林可增强L THP的镇痛作用
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| 关 键 词： | 阿米替林 左旋四氢巴马汀 镇痛作用 热板法 化学刺激法 |
| 文章编号： | 1007-306(2003)05-66-03 |
| 修稿时间： | 2003-05-13 |
Amitriptyline Increased Analgesic Effect of L-tretrahydropalmatine |
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| Chen Ping,Chen Penzhen,Yuan Yaoping. Amitriptyline Increased Analgesic Effect of L-tretrahydropalmatine[J]. Pharmacertical and Clinical Research, 2003, 11(5): 66-68 |
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| Authors: | Chen Ping Chen Penzhen Yuan Yaoping |
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| Affiliation: | Wuxi 214063 |
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| Abstract: | Objective To study the analgesic effect of the amitriptyline increased L tretrahydropalmatine. Methods the analgesic effect was judged using the hot plate and writhing test in mice. Results The result showed that amitriptyline (4 2 mg/kg , 8 3 mg/kg) has obviously enhanced the analgesic effect of L tretrahydropalmatine . However the time of the analgesic effect was lasting for 4 h. Conclusion Amitriptyline increased analgesic effect of L tretrahydropalmatine . |
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| Keywords: | Amitriptyline L tretrahydropalmatine Analgesic effect Hot plate test Writhing test |
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