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正交试验优选扶阳软坚清脉方的提取工艺
引用本文:常锦明 宋清宏 曹烨民 魏 莉. 正交试验优选扶阳软坚清脉方的提取工艺[J]. 世界中医药, 2014, 9(1): 95-98
作者姓名:常锦明 宋清宏 曹烨民 魏 莉
作者单位:[1] 上海中医药大学中药学院,上海201203 [2] 上海市中医老年医学研究所,上海200031 [3] 上海市中西医结合医院脉管科,上海200082
基金项目:上海市卫生局中药新药及院内制剂研发项目(编号:2011xY005)
摘    要:目的:优化软坚清脉方的最佳提取工艺。方法:以奇壬醇、肉桂酸及得膏率为指标,采用正交试验,利用多指标综合评价的方法及对权重系数的设置,优选最佳提取工艺。结果:处方药材最佳提取工艺为加8倍量的水,浸泡0.5 h,提取3次,2 h/次。结论:该提取工艺科学、稳定、可行。

关 键 词:软坚清脉方  奇壬醇  肉桂酸  正交试验  提取工艺
收稿时间:2013-04-23

Optimal Extraction Technology for Ruanjian Qingmai decoction by Orthogonal Test
Chang Jinming,Song Qinghong,Cao Yemin,Wei Li. Optimal Extraction Technology for Ruanjian Qingmai decoction by Orthogonal Test[J]. World Chinese Medicine, 2014, 9(1): 95-98
Authors:Chang Jinming  Song Qinghong  Cao Yemin  Wei Li
Affiliation:1 Shanghai University of TCM, Shanghai 201203, China ; 2 Shanghai Geriatric Institute of Chinese Medicine, Shanghai 20003l, China; 3 Combine Traditional Chinese and Western Medicine Hospital of Shanghai, Shanghai 200082, China)
Abstract:Objective:To establish the optimal extraction technology for Ruanjian Qingmai decoction .Methods:With the extraction rate and the content of Qirenchun and Cinnamic acid as indexes , choose the best extraction technology by orthogonal design .Results: The best extraction process was as follow:the ratio of sample to water was 1:8, soaking for 0.5 hours, extracting for 2 hours, 3 times of ex-traction.Conclusion:The optimal extraction technology is rational , stable and feasible .
Keywords:Ruanjian Qingmai decoction  Qirenchun  Cinnamic acid  Orthogonal test  Extraction technology
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