In vitro efficacy of the combination of ciprofloxacin and cefotaxime against Vibrio vulnificus |
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| Authors: | Kim Dong-Min Lym Yong Jang Sook Jin Han Hulin Kim Young Gi Chung Choon-Hae Hong Soon Pyo |
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| Affiliation: | Department of Laboratory Medicine, Chosun University Medical School, 588 Seoseok-dong, Dong-gu, Gwang-Ju 501-717, South Korea. |
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| Abstract: | We performed time-kill studies of antimicrobial combinations that included minocycline, cefotaxime, and ciprofloxacin with Vibrio vulnificus ATCC 27562. Cefotaxime-plus-ciprofloxacin combinations acted synergistically against V. vulnificus in vitro, and this combination regimen can be a good choice as the empirical treatment for suspected necrotizing fasciitis due to V. vulnificus. |
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