缬沙坦对社区老年原发性高血压的疗效评价

目的研究分析缬沙坦对社区老年原发性高血压患者的治疗效果。方法将社区老年原发性高血压患者70例随机分为观察组和对照组,各35例。观察组使用缬沙坦行降压治疗,对照组使用氯沙坦行降压治疗。治疗12周后,分析两组治疗前后血压情况以及血常规、尿常规、肝肾功能等指标。结果两组治疗后收缩压和舒张压均较治疗前明显下降(P0.05或P0.01);两组治疗后收缩压和舒张压比较,观察组均低于对照组(P0.01);观察组的总有效率高于对照组(χ2=4.20,P0.05)。未出现严重并发症。结论缬沙坦降压效果明显,副作用少,价格便宜,服用方便,患者依从性好。尤其适合于老年高血压患者,值得临床推广应用。

Clinical evaluation of valsartan in treating the elderly patients with essential hypertension

Objective To study and analyze the therapeutic efficacy of using valsartan to treat the elderly patients with essential hypertension.Methods Seventy cases of elderly patients with essential hypertension in our community were randomly divided into the observation group and control group.Patients in observation group were treated with valsartan for antihypertensive treatment,while patients in the control group treated with losartan for antihypertensive treatment. After 12 weeks of treatment,indexes analysis of blood pressure,blood,urine,liver and kidney function before and after treatment was performed.Results After treatment, the contractive pressure and diastolic pressure of the patients in both groups were obviously lower than those of before treatment（P0.05 or P0.01）.The contractive pressure and diastolic pressure of the patients in observation group were lower than those of the control group（P0.01）and the total effective rate of the observation group was higher than that of the control group（χ2=4.20,P0.05）. No serious complications occurred.Conclusion Valsartan has the advantages of obvious effect,fewer side effects,lower price, being convenient to be taken and good patient compliance,and is especially suitable for elderly patients with hypertension and is worthy of clinical application.