酪蛋白磷酸肽-磷酸钙溶液体外再矿化作用的化学分析及显微硬度测试

目的研究酪蛋白磷酸肽-磷酸钙溶液在体外对牛牙釉质早期人工龋的再矿化作用。方法用不同浓度的酪蛋白磷酸肽-磷酸钙（CPP—CP）溶液对牛牙釉质早期人工龋进行再矿化处理后，首先采用化学分析法测量处理液中的残余矿物质，得出沉积在龋损区内的矿物质含量；然后采用显微硬度法测量处理前后牙釉质剖面硬度变化。结果CPP—CP溶液可以在体外使龋损牙釉质发生再矿化，再矿化作用与CPP—CP浓度呈剂量-效应关系。再矿化后龋损区矿物沉积量与再矿化液的CPP—CP浓度成正比。结论酪蛋白磷酸肽-磷酸钙溶液能凭借高钙磷浓度梯度促进牛牙釉质早期人工龋的再矿化。

Chemical analysis and microhardness test of the remineralization of casein phosphopeptides stabilized calcium phosphate to bovine enamel caries in vitro

Objective To assess the remineralization ability of casein phosphopeptides stabilized calcium phosphate to bovine enamel caries in vitro. Methods Various concentrations of CPP - CP were used to remineralize bovine enamel with early artificial caries lesion for ten days. Residual calcium and phosphate were analysed by chemical analysis, The enamel blocks were cut and subjected to microhardness test. Results All of the solutions were able to deposit the minerals into the bodies of the lesions. The remineralization ability was correlated with the CPP - ACP concentration. Conclusion CPP- CP can promote remineralization of bovine with early artificial caries caries. The remineralization ability of CPP- CP depends on its high concentration of calcium phosphate.