MALE PSEUDOHERMAPHRODITISM IN A PATIENT WITH E-TRISOMY SYNDROME

A newborn patient with E-triso my syndrome and male pseudohermaphroditism is described. At autopsy the internal genital organs were found to be ambiguous with a bicornuate uterus and rudimentary Fallopian tubes. The testes and epididymis showed normal gross and microscopic appearance, while the deferential ducts were hypoplastic and ended as Gärtner's canals on both sides of the rudimentary utero-vaginal canal. The failure of the embryonic testes to sup press the Müllerian ducts in this patient is probably not a result of the genetic imbalance caused by the chromosome aberration, but rather a fortuitous event related to the phenomenon encountered in the uterine hernia syndrome.