骶神经根对直肠肛门功能选择性支配的实验研究

研究骶神经根对直肠和肛门功能的选择性支配，为临床从骶神经根角度重建脊髓损伤后的排便功能障碍提供依据。方法：对７只ＳＣＩ犬进行硬膜外Ｌ７－Ｓ３神经根电刺激，用二导程测压仪同时记录直肠和肛门的压力变化。结果：犬直肠的神经支配以Ｓ２为主，Ｓ１，Ｓ３次之；肛门的神经支配以Ｓ３为主，Ｓ１，Ｓ２次之。

Selective innervation of the rectum and anal sphincter by sacral roots: a canine electrostimulation study

Objective: To investigate whether there is a dominant sacral root to the motive function of rectum and anal sphincter, and provide experimental basis for neural reconstruction of defaecation in spinal cord injured (SCI) patients. Methods: Seven spinal cord injured mongrel dogs were included in the study. After L 4 L 7 laminectomy, the bilateral L 7 S 3 roots were electrostimulated separately and rectal and sphincter pressure were recorded synchronously. Results: For rectal innervation, S 2 is the most dominant, S 1 and S 3 contribute to a smaller extent. For sphincter, S 3 is the most dominant, S 1 and S 2 contribute lesser but still significant extent. Above 85% L 7 roots provide some functional contribution to rectum and anal sphincter. For both rectum and sphincter, the right sacral roots provide more contribution than the left ones. Conclusion: The functional innervation to the rectum and anal sphincter have a minor dominance but a major overlapping among different sacral roots. Its potential significance in restoration of controlled defaecation in SCI patients is discussed.