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高血压病患者心血管功能变化特点的研究
引用本文:李琛,谢江柳. 高血压病患者心血管功能变化特点的研究[J]. 中国医药, 2012, 7(8): 931-933
作者姓名:李琛  谢江柳
作者单位:625000,四川省雅安市人民医院心内科
摘    要:目的 应用脉搏波检测技术探讨高血压病患者心血管功能的改变.方法 将106例高血压病患者按血压水平分为高血压病1、2、3级组,并将62例健康体检者设为正常对照组,分别检测各组心血管功能.结果 与正常对照组相比,高血压病组、高血压病1级组、高血压病2级组、高血压病3级组患者的每搏输出量[(114±25)ml、(117±24)ml、(111±21)ml、(112±31)ml比(95±25)ml]、心脏指数[(5.1±0.9)L/min·m2、(5.2±0.8)L/min·m2、(5.4 ±0.8)L/min·m2、(4.8 ±0.8)L/min·m2比(4.6±1.0)L/min·m2]、左心室舒张末压[(18±7)mm Hg(1mm Hg=0.133 kPa)、(15±6)mm Hg、(20±4)mm Hg、(20±8)mm Hg 比(12±4)mm Hg]、肺毛细血管楔嵌压[(18±7)mm Hg、(15±6)mm Hg、(20±4)mm Hg、(20±8)mm Hg比(12 ±4)mm Hg]、平均动脉压[(131±16)mm Hg、(119±6)mm Hg、(132±8)mm Hg、(151±13)mm Hg比(95±11)mm Hg]、肺动脉压[(30±11)mm Hg、(26±10)mm Hg、(33 ±7)mm Hg、(34±13)mm Hg比(20±7)mm Hg]、还原血黏度[(4.33±0.94)mPa·s、(4.10±0.85)mPa·s、(3.95±0.69)mPa·s、(5.08±0.90)mPa·s比(3.76±0.73)mPa·s]等均增高(P<0.05);血管弹性扩张系数[(0.65±0.34)、(0.68±0.35)、(0.57±0.22)、(0.66±0.40)比(0.49±0.28)]、血管顺应度[(1.10±0.31)、(1.30±0.29)、(0.94±0.15)、(0.90±0.23)比(1.39±0.21)]较正常对照组明显降低(P<0.01).结论 脉搏波检测技术作为临床心血管功能的检验手段之一,具有一定的应用价值.

关 键 词:高血压病  心血管功能  脉搏波

Study of cardiac function in patients with essential hypertension
LI Chen , XIE Jiang-liu. Study of cardiac function in patients with essential hypertension[J]. China Medicine, 2012, 7(8): 931-933
Authors:LI Chen    XIE Jiang-liu
Affiliation:. Department of Cardiovascular Medicine, Yaan People's Hospital, Sichuan Province, Yaan 625000, China
Abstract:Objective To study the cardiac function in patients with essential hypertension(EH) by pulse wave examination technology. Methods Totally 106 patients with EH were studied by pulse wave examination technology. They were divided according to blood pressure level into mild, moderate and high blood pressure group. Sixty-two subjeccts with normal were studied as controls. Results Stroke volume [ (114 ±25)ml,(117 ±24)ml,(111 ± 21 ) ml, ( 112 ± 31 ) ml compared with (95 ± 25 ) ml ], cardiac index [ ( 5. 1 ± 0. 9) L/min . m2, ( 5.2 ± 0. 8 ) L/min . m2, (5.4 ± 0.8 ) L/min . m2, (4.8 ± 0.8 ) L/min. m2 compared with (4.6 ± 1.0 ) L/min . m2 ] ,left ventricular end diastolic pressure [(18 ±7)mm Hg(1 mm Hg =0. 133 kPa) ,(15 ±6)mm Hg, (20 ±4)mm Hg, (20 ±8) mm Hg compared with( 12 ± 4) mm Hg ], pulmonary artery wedge pressure [ ( 18 ± 7 ) mm Hg, ( 15 ± 6 ) mm Hg, ( 20 ± 4) mm Hg, ( 20 ± 8 ) mm Hg compared with ( 12 ± 4) mm Hg ], mean artery pressure [ ( 131 ± 16) mm Hg, ( 119 ± 6) mm Hg, (132 ± 8 )mm Hg, (151 ± 13 )mm Hg compared with (95 + 11 )mm Hg], pulmonary artery pressure [ (30 ± 11 ) mm Hg, (26 ± 10) mm Hg, (33 ±7) mm Hg, (34 ± 13) mm Hg eompared with(20±7 ) mm Hg] , deoxidize blood viscosity [ (4.33 ± 0.94) mPa . s, (4.10 ± 0.85 ) mPa .s, ( 3.95 ± 0.69 ) mPa . s, ( 5.08 ±0.90 ) mPa . s compared with (3.76 ±0.73 )mPa . s ] and other indexes of cardiac function were all significantly higher in EH patients than those in controls(P 〈0.05). Artery flexibility expansion eoefficient [ (0. 65 ±0.34), (0. 68 ±0. 35), (0. 57 ±0.22 ), ( 0.66 ± 0.40 ) compared with ( 0.49 ± 0.28 ) ], artery compliance [ ( 1.10 ± 0.31 ), ( 1.30 ± 0.29 ) , (0.94 ± 0.15 ) , ( 0.90 ± 0.23 ) compared with ( 1.39 ± 0.21 ) ] and the indexes of artery stiffness degree were all significantly worse in EH patients (P 〈0.01 ). Conclusion Pulse wave examination technology can offer useful parameters for cardiac function in patients with EH.
Keywords:Hypertension  Cardiac function  Pulse wave
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