社区卫生服务中心应用抗菌药物的回顾性分析

目的 了解社区卫生服务中心抗菌药物应用情况,为抗菌药物的临床合理应用和规范管理提供参考依据.方法 收集北京市海淀区万寿路社区卫生服务中心2011年1-12月处方2000份,对抗菌药物的应用情况进行回顾性分析,按照实施抗菌药物规范化应用和管理措施培训前后,将处方分为培训前组和培训后组,各1000例患者.结果 培训前组与培训后组抗菌药物使用率分别为46.7％(467份)和24.4％(244份),培训后组的药物选择不合理率和未进行标本培养及药敏试验率、药物联用不合理率明显低于培训前组,差异有统计学意义[分别为25.0％ (61/244)比58.5％(273/467),P＜0.01；15.1％ (37/244)比36.8％(172/467),P＜0.01；5.7％ (14/244)比12.4％(58/467),P＜0.05].结论 抗菌药物使用率较高,且存在一些不合理应用现象.医院及社区应加强监管,以促进临床合理使用抗菌药物.

Retrospective analysis of the use of antibacterial drugs in the community health service center

Objective To investigate the utilization of antibacterial drugs in the community health service center to provide clinical references for the standard management of antibacterials, and to promote rational drug use. Methods Totally 2000 case in our community health service center between January, 2011 and December 2011 were randomly selected for the retrospective analysis of the use of antibacterials; 1000 patients who were discharged randomly before June 30th were chosen as control group, and those who were discharged randomly after June 30th were chosen as study group. Results Antibiotics use in the control group and study group was 46.7% and 24.4% with statistical significance（ P 〈 0.05） ; irrational use of antimicrobial drugs was 58.5% and 25.0% with statistical significance （ P 〈 0.05 ）. Conclusions The application rate of antibacterials is high. Therefore, we should strengthen the management of antimicrobial drugs in order to promote the rational use of antimicrobial drugs.