兰索拉唑与奥美拉唑治疗胃食管反流病的比较观察

目的比较兰索拉唑与奥美拉唑治疗胃食管反流病的疗效。方法将我院2010年1月至2011年6月确诊为胃食管反流病的98名患者随机分为兰索拉唑组和奥美拉唑组,分别服用兰索拉唑30mg/日,奥美拉唑20mg/日,疗程4周,疗程结束后比较症状与胃镜检查结果。结果兰索拉唑组的有效率为95.92%,奥美拉唑组的有效率为79.59%,通过χ2检验,两组有显著性差异,P<0.01。结论兰索拉唑对胃食管反流病的疗效优于奥美拉唑。

Comparison Observation of Lansoprazole and Omeprazole Treatment of Gerd

Objective Lansoprazole is compared with omeprazole treatment of gastroesophageal reflux disease. Methods 98 patients who diagnosed with gastroesophageal reflux in our hospital from January 2010-June 201 t were randomized into lansoprazole group and omeprazole group, respectively take 30 mg/day lansoprazole and omeprazole 20 rag/day, four weeks of treatment, symptoms after treatment compared with gastroscope inspection results. Results Lansoprazole was the effective rate of 95.92%, omeprazole group of effective rate of 79.59%, through the chi-square test, a significant difference between the two groups, P〈0.01. Conclusion Lansoprazole was gastroesophageal reflux disease better therapeutic omeprazole.