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手术减肥治疗对肥胖患者血清C反应蛋白水平的影响
引用本文:姜南,陈玉浩,陈言汤,孟宪星,李媛,王丽娟,许亚红. 手术减肥治疗对肥胖患者血清C反应蛋白水平的影响[J]. 郑州大学学报(医学版), 2004, 39(3): 497-499
作者姓名:姜南  陈玉浩  陈言汤  孟宪星  李媛  王丽娟  许亚红
作者单位:河南省职业病防治研究所河南省整形美容研究中心,郑州,450052;郑州大学第一附属医院整形外科,郑州,450052
摘    要:目的研究手术减肥配合低热量饮食治疗对肥胖患者血清C反应蛋白(CRP)水平的影响.方法测定42例手术治疗的单纯性肥胖患者在治疗0周和25周时的体重、腰臀围、血压,同时测定空腹血糖、脂代谢参数、胰岛素、CRP值.结果治疗25周后患者平均血压、空腹血糖、胆固醇及胰岛素抵抗指数均较治疗前明显降低(P<0.05),体重下降>5%者,CRP水平较治疗前明显下降(P<0.01).结论外科手术减肥配合低热量饮食治疗能够有效降低单纯性肥胖患者的体重及CRP水平,不同程度地改善代谢水平,从而降低心血管疾病的患病率及危险性.

关 键 词:手术减肥  心血管疾病  C反应蛋白
修稿时间:2003-06-18

Effects of weight-reducing by operation on serum C-reactive protein levels in obese patients
JIANG Nan ),CHEN Yuhao ),CHEN Yantang ),MENG Xianxing ),LI Yuan ),WANG Lijuan ),XU Yahong ) )Henan Institute of Occupational Medicine,Henan Plastic Cosmetic Research Center,Zhengzhou ). Effects of weight-reducing by operation on serum C-reactive protein levels in obese patients[J]. Journal of Zhengzhou University: Med Sci, 2004, 39(3): 497-499
Authors:JIANG Nan )  CHEN Yuhao )  CHEN Yantang )  MENG Xianxing )  LI Yuan )  WANG Lijuan )  XU Yahong ) )Henan Institute of Occupational Medicine  Henan Plastic Cosmetic Research Center  Zhengzhou )
Affiliation:JIANG Nan 1),CHEN Yuhao 1),CHEN Yantang 2),MENG Xianxing 1),LI Yuan 1),WANG Lijuan 1),XU Yahong 1) 1)Henan Institute of Occupational Medicine,Henan Plastic Cosmetic Research Center,Zhengzhou 450052 2)Department of Plastic Surgery,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052
Abstract:Aim:To study the effects of weight reducing by operation combined with hypocaloric diet on plasm C reactive protein(CRP) level in obese patients. Methods: A total of 42 obese patients were peformed weight reducing operation.Before and after 25 week treatment,the body weight,lumbar sciatic line,blood pressure,fasting blood sugar,lipometabolism parameters,insulin and CRP were determined.Results: After treatment, the average blood pressure,fasting blood sugar,cholesterin and insulin resistant index reduced compared with the stage before treatment( P <0.05).Serum CRP level in patients with weight reducing by 5%or more decreased significantly compared with the stage before treatment( P < 0.01 ).Conclusion:Weight reducing by operation combined with hypocaloric diet can effectively reduce the body weight and CRP level of obese patients,improve metabolism level,thus decreasing the incidence of cardiovascular diseases.
Keywords:weight reducing by operation  cardiovascular disease  C reactive protein
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