| 牙龈成纤维细胞、牙周膜细胞对白细胞介素8的趋化反应 |
| |
| 引用本文： | 栾庆先,曹采方,涉谷俊昭,牧克教,岩山幸雄. 牙龈成纤维细胞、牙周膜细胞对白细胞介素8的趋化反应[J]. 中华口腔医学杂志, 2001, 36(1): 40-41 |
| |
| 作者姓名： | 栾庆先 曹采方 涉谷俊昭 牧克教 岩山幸雄 |
| |
| 作者单位： | 1. 北京大学口腔医学院牙周科
2. 日本朝日大学齿学部齿周病学讲座 |
| |
| 摘 要： | 目的评价牙龈成纤维细胞、牙周膜细胞对白细胞介素8（interleukin-8,IL-8）的趋化反应。方法将体外培养第6代的牙龈成纤维细胞和牙周膜细胞（2.5×10
|
| 关 键 词： | 白细胞介素8 成纤维细胞 趋化因子 牙龈 牙周膜 |
| 修稿时间： | 2000-03-15 |
The chemotactic response of gingival fibroblasts and periodontal ligament cells to interleukin-8 |
| |
| LUAN Qingxian ,TOSHIAKI Shibutani,KATSUNORI Maki,et al ?. The chemotactic response of gingival fibroblasts and periodontal ligament cells to interleukin-8[J]. Chinese journal of stomatology, 2001, 36(1): 40-41 |
| |
| Authors: | LUAN Qingxian TOSHIAKI Shibutani KATSUNORI Maki et al ? |
| |
| Affiliation: | Department of Periodontology, Peking University School of Stomatology, Beijing 100081, China. |
| |
| Abstract: | OBJECTIVE: To evaluate the chemotactic response of gingival fibroblasts and periodontal ligament cells to interleukin-8. METHODS: The passage 6 cultured gingival fibroblasts and periodontal ligament cells (2.5 x 10(8) cell/L, respective) were placed in the upper compartment of the Transwell cell culture chamber. The lower compartment contained IL-8 with the concentrations of 10(-10), 10(-9), 10(-8), 10(-7) mol/L, respectively. Incubation was at 37 degrees C in an atmosphere of 95% air and 5% CO2 for 24 h. The number of migrated cells were counted under high power fields. RESULTS: IL-8 at concentrations ranged from 10(-9)-10(-7) mol/L promoted the chemotactic movement of gingival fibroblasts in a dose-dependent manner. However, at the same IL-8 concentrations the chemotactic movement of periodontal ligament cells was not elevated. CONCLUSION: IL-8 may play its role in regulating chemotaxis of gingival fibroblast. |
| |
| Keywords: | Interleukin 8 Fibroblast Chemotactic factors |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
