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Whoonga: Potential Recreational Use of HIV Antiretroviral Medication in South Africa
Authors:David J. Grelotti  Elizabeth F. Closson  Jennifer A. Smit  Zonke Mabude  Lynn T. Matthews  Steven A. Safren  David R. Bangsberg  Matthew J. Mimiaga
Affiliation:1. Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA
6. Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
2. The Fenway Institute, Fenway Health, Boston, MA, USA
3. Maternal, Adolescent and Child Health (MatCH), Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa
4. Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
5. Massachusetts General Hospital Center for Global Health, Boston, MA, USA
7. Ragon Institute of MGH, MIT and Harvard, Boston, MA, USA
Abstract:Whoonga is a drug cocktail in South Africa rumored to contain illicit drugs and HIV antiretroviral (ARV) medication. Although its use may adversely impact adherence to HIV treatment and may have the potential to generate ARV resistance, there is a paucity of research characterizing whoonga. We learned of whoonga during semi-structured interviews about substance abuse and HIV risk at “club-events” known as inkwaris in an urban township of Durban, South Africa. Whoonga was an emerging theme spontaneously identified as a problem for the community by 17 out of 22 informants. Perceptions of whoonga suggest that it is highly addictive, contains ARVs (notably efavirenz), is used by individuals as young as 14, and poses a threat to the health and safety of those who use it, including increasing the risk of HIV infection. Our informants provide preliminary evidence of the dangers of whoonga and reinforce the need for further study.
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