不同种类手消毒剂对脊髓灰质炎病毒灭活效果的实验观察

目的观察不同种类手消毒剂对脊髓灰质炎病毒的灭活效果。方法采用悬液定量试验法和载体定量试验法进行了实验室观察。结果含有效碘4 500 mg/L的聚维酮碘消毒液在清洁条件下作用10 min,对悬液内脊髓灰质炎病毒灭活对数值>4.00;在有机干扰物存在的条件下作用15 min,对悬液内脊髓灰质炎病毒灭活对数值>4.00。含体积分数70%乙醇与10 g/L过氧化氢的手消毒液在清洁条件下作用15 min,对悬液内脊髓灰质炎病毒灭活对数值>4.00;在有机干扰物存在的条件下作用30 min,对悬液内脊髓灰质炎病毒灭活对数值>4.00。含体积分数70%乙醇与10 g/L氯己定的手消毒凝胶作用3 min,对载体上脊髓灰质炎病毒灭活对数值>4.00。结论乙醇氯己定手消毒凝胶可以快速灭活载体上脊髓灰质炎病毒,聚维酮碘消毒液与乙醇过氧化氢手消毒液有效灭活悬液内脊髓灰质炎病毒需要10 min以上。

EXPERIMENTAL OBSERVATION ON THE INACTIVATION EFFICACY OF DIFFERENT HAND ANTISEPTICS ON POLIOVIRUS

Objective To observe the inactivation efficacy of different hand antiseptics on poliovirus.Methods The suspension quantitative germicidal method and carrier quantitative germicidal method were used in this study to carry out the experimental observation.Results The average killing logarithm values of poliovirus in suspension was >4.00 exposed to the povidone iodine antiseptic containing available iodine 4 500 mg/L for 10 min under clean condition,While it was >4.00 for 15 min under interfering substances condition.The average killing logarithm values of poliovirus in suspension was >4.00 exposed to the 70%(v/v) alcohol and 10 g/L hydrogen peroxid compound for 15 min under clean condition,however it was >4.00 for 30 min under interfering substances condition.The average killing logarithm values of poliovirus on carrier was >4.00 exposed to the 70%(v/v) ethyl alcohol and 10 g/L chlorhexidine compound hand antiseptic gel for 3 min.Conclusion The compound hand antiseptic containing ethyl alcohol and hydrogen peroxid can quickly inactivate poliovirus on carrier and the killing time of poliovirus in suspension exposed to the povidone iodine and ethyl alahol hydrogen peroxid compound exceeds 10 min.