胶原膜与羟基磷灰石修复牙槽骨缺损的远期疗效观察

目的：观察国产BME-10X型医用胶原膜与羟基磷灰石(HA)联合引导组织再生治疗牙周炎、根尖囊肿造成骨缺损的I临床疗效。方法：选择18例患者的9颗Ⅱ度根分叉病变牙的9个位点、11颗近远中二、三壁骨下袋牙的16个位点、6颗根尖囊肿牙，在骨缺损区填入HA后，用胶原膜覆盖，观察1年以上的愈合情况。结果：骨下袋病变成功率75％，根分叉病变成功率77.8％，根尖囊肿成功率100％。结论：胶原膜／HA引导再生术在牙槽骨缺损修复中有一定应用价值。

Experience of repairing alveolar bone defects by collagen membrane and hydroxyapatite and its long-term result

PURPOSE: To observe the clinical effect of using the domestic BME-10X medical collagen membrane and hydroxyapatite (HA) in guide tissue regeneration of the bone defects caused by periodontitis and periapical cyst. METHODS:18 cases with 9 points in 9 teeth with II degree furation involvement, 16 points in 11 teeth with 2 or 3 bone bottom pockets and 6 cases with periapical cyst were chosen in our study.The defect region of alveolar bone was stuffed with HA and covered with collagen membrane.The pathological changes after over one year were observed and recorded. RESULTS: The pathological changes of alveolar bone defects were significant in 7 cases with furcation involvements (77.8%),12 cases with bone bottom pockets (75%),and 6 cases of periapical cyst (100%).CONCLUSION: The combination of collagen membrane and HA can be applied in repairing the alveolar bone defects resulting form periodontitis and periapical cysts.