| 老年脑白质疏松与血清同型半胱氨酸水平关系的临床研究 |
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| 引用本文： | 刘平,姜树军,汪丽芳,苏宁,李艳霞. 老年脑白质疏松与血清同型半胱氨酸水平关系的临床研究[J]. 解放军医学高等专科学校学报, 2011, 0(3): 515-516 |
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| 作者姓名： | 刘平 姜树军 汪丽芳 苏宁 李艳霞 |
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| 作者单位： | [1]解放军海军总医院干部病房神经内科,北京100048 [2]解放军261786部队门诊部,北京100094 |
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| 摘 要： | 目的探讨血浆同型半胱氨酸（Hcy）与老年脑白质疏松症（LA）的相关性,了解脑白质疏松症的危险因素。方法 182例老年患者根据CT/MRI结果按有无脑白质疏松,分为LA组95例和非LA组87例,采用循环酶法对两组患者血浆Hcy的浓度进行测定。结果 LA组Hcy浓度（21.13±4.62）μmol/L明显高于非LA组（15.36±4.58）μmol/L,两组比较差异有统计学意义（P〈0.01）。结论血清同型半胱氨酸水平与老年脑白质疏松关系密切,高同型半胱氨酸血症（Hhcy）是脑白质疏松症的一个独立危险因素。
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| 关 键 词： | 脑白质疏松症 同型半胱氨酸 危险因素 |
Relativity study on leukoaraiosis and homocysteine for elderly inpatients |
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| Liu Ping,Jiang Shu-jun,Wang Li-fang,Su Ning,Li Yan-xia. Relativity study on leukoaraiosis and homocysteine for elderly inpatients[J]. Clinical Journal of Medical Officer, 2011, 0(3): 515-516 |
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| Authors: | Liu Ping Jiang Shu-jun Wang Li-fang Su Ning Li Yan-xia |
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| Affiliation: | 1.Cadre Wards Department of Neurology,Navy General Hospital of PLA,Beijing 100048,China;2.Department of Outpatient,the 61786 Force of PLA,Beijing 100094,China) |
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| Abstract: | Objective To investigate the relation between leukoaraiosis（LA） and homocysteine（Hcy） levels in elderly inpatients,and identify the risk factors associated with leukoaraiosis.Methods A total of 182 elderly inpatients were divided into the group of LA（n=95） and the group of non-LA（n=87） according to CT/MRI findings with or without leukoaraiosis.The Hcy levels were analyzed in all patients.Results The Hcy levels in LA groups（21.13±4.62） μmol/L was higher than that of non-LA groups（15.36±4.58）μmol/L,the difference between two groups had statistical significance（P0.01）.Conclusion Homocysteine were close related to leukoaraiosis.It suggested that hyperhomocysteinemia（Hhcy） may be independent risk factor of leukoaraiosis. |
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| Keywords: | leukoaraiosis homocysteine risk factors |
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