小牛脾提取物在中晚期宫颈癌同步放化疗中的作用

目的评价小牛脾提取物在中晚期宫颈癌患者同步放化疗中保护骨髓和改善患者生活质量的作用。方法对照组30例给予常规放疗并DF方案同步化疗,治疗组30例在对照组治疗的基础上给予小牛脾提取物（10 ml/d）;观察两组患者毒副反应发生率和生活质量情况。结果治疗组血液学毒性发生率低于对照组（P〈0.05）;治疗组患者生活质量改善优于对照组（P〈0.01）。未见小牛脾提取物所致的严重毒副作用。结论 小牛脾提取物对接受同步放化疗的宫颈癌患者在保护骨髓和提高生活质量等方面具有明显作用。

Effects of sipulin in concurrent radiochemotherapy for the patients with advanced cervical carcinoma

Objective To evaluate the effects of Sipulin in protecting marrow,decreasing digestive tract reaction and improving the quality of life in the patients with advanced cervical carcinoma treated with concurrent radiochemotherapy.Methods Thirty patients were performed with routine radiotherapy combined with DF protocol concurrent chemotherapy in the control group.Sipulin（10 ml·d-1） was administered on the basis of the treatment in the control group.Incidence of toxic and adverse reaction,qualities of life in patients of two groups were observed.Results Rate of hematological toxicity in the treatment group was lower than that in the control group（P0.05）.Quality of life was improved better in treatment group than that in the control group（P0.01）.Severe toxic and adverse effects induced by Sipulin didn＇t occur.Conclusion Sipulin has remarkable effects in protecting marrow and improving the quality of life in the patients with advanced cervical carcinoma treated with concurrent radiochemotherapy.