血运重建对非ST段抬高急性冠脉综合征患者生活质量的影响

目的探讨血运重建对非ST段抬高急性冠脉综合征（NSTE-ACS）患者生活质量的影响。方法将559例NSTE-ACS患者分为完全血运重建组（完全介入治疗组、冠脉搭桥手术组）、不完全血运重建组（不完全介入治疗组）、单纯药物治疗组,通过SF-36生活质量量表随访2年患者的生活质量变化。结果 （1）经过2年的随访调查,发生重大心血管事件的有111例。（2）在SF-36量表中的各个维度改善情况显示,单纯药物治疗组对各个维度的改善率普遍偏低,且与其他三组相比,差异有统计学意义（P〈0.01或P〈0.05）;而在躯体疼痛、社会功能、情感职能、精神健康、健康变化5个维度中,完全介入治疗组改善率优于冠脉搭桥手术组（P〈0.05）。结论完全冠状动脉血运重建可显著改善NSTE-ACS患者远期的生活质量,完全介入治疗对躯体疼痛的改善率最高;冠状动脉搭桥对生理职能改善率最高。

The impact of coronary artery revascularization on the patient with non-ST segment elevation acute coronary syndrome

Objective To investigate the impact of coronary artery revascularization on the patient with non-ST segment elevation acute coronary syndrome （NSTE-ACS）. Methods 559 patients who admitted to hospital with a diasnusis of non-ST segment elevation acute coronary syndrome were divided into complete revascularization group （ intervention group and coronary artery bypass group）, incomplete revascularization group （ incomplete intervention group）, and simple drug treatment group and were analysed at baseline with 2 years d fullow-up. In the mean time, a corresponding table was made accordin8 to the SF-36 to follow up their Quality of Life （QOL）.Resuits （1）Severecardiovascularevontsoceurredin 111 casesdudng 2 years follow-up. （2）Theimprovementof various dimensions in SF-36 scale showed that The improvement rates of various dimensions in simple drug treatment group were general on the low side, compared with the other three groups, difference had statistical sisnificanco （ P 〈 0.01 or P 〈 0.05 ） ; in five dimensions of bodily pain, social function, emotional function, mental health and health change, improvement rate in interven- tion group excelled to coronary artery bypass group （ P 〈 0.05 ）. Conclustion Complete coronary artery rovnsculerilation can im- prove the QOL in the patients with non-ST segment elevation acute coronary syndrome. Complete intervention treatment has the highost improvement rate for bodily pain; coronary artery bypass has the highest improvement rate for physiological functions.