脐血流检测妊高征及胎儿宫内发育迟缓的研究

目的:分析彩色多普勒超声脐血流检测妊高征(PIH)及胎儿宫内发育迟缓(IUGR)等病理情况时脐动脉血流的变化。方法:采用脐血流检测仪对148例正常孕妇及32例PIH、30例IUGR孕妇进行收缩期最大血流速度/舒张期末血流速度的比值(S/D)、阻力指数(RI)、波动指数(PI),快速血流量比(FVR)的测定。结果:IUGR组病例S/D比值、PI,RI值均明显高于正常组(P<0.01),FVR值明显低于正常组(P<0.05);妊高征组S/D比值、PI、RI值有明显增高的趋势(P<0.01),FVR值下降,有统计学差异(P<0.05)。结论:脐血流检测是预测胎儿宫内状况的一种安全、可靠、实用的监测方法,及时判断胎儿宫内安危对于指导PIH及IUGR的治疗和预后具有重要的临床实用价值。

Study on the Detection of Pregnancy Induced Hypertension and Intrauterine Growth Retardation Using Fetal Umbilical Blood Flow Detector

Objective: To detect and analyse the changes of blood flow of umbilical artery in pregnancy induced hypertension (PIH) and in intrauterine growth retardation (IU-GR) by color Doppler ultrasound technique. Methods: Umbilical Blood Flow Detector was used to detect the ratio of S/D, RI, PI and FVR of 148 healthy pregnant women and 32 PIH and 30 IUGR pregnant women. Results: The ratio of S/D, PI, RI of IUGR group were all significantly higher than those of control group (P<0.01), FVR of IUGR group was signifcantly lower than that of control group (P < 0. 05). There was a great increase in the ratio of S/D , PI, and RI of PIH group (P<0.01), and a decrease in FVR(P<0.01),and there was a statistical difference(P<0.05) .Conclusion:Umbilical blood flow detection is a safe, reliable, and practical mornitoring method of predicting intrauterine fetal condition, it is of great value in guiding the treatment of PIH and IUGR.