子痫前期患者超敏C-反应蛋白和D-二聚体检测的临床意义

目的：探讨子痫前期患者血清超敏C-反应蛋白（hs-CRP）和D-二聚体（DD）检测的临床价值。方法：选择子痫前期孕妇62例（其中病情为轻度34例,重度28例）,正常妊娠晚期孕妇35例,以及体检健康非孕妇女32例（对照组）,分别对入选对象进行血清hs-CRP和DD水平的测定。结果：子痫前期重度组、轻度组和正常妊娠组血清hs-CRP和DD水平均显著高于对照组（P〈0.01）,子痫前期重度组、轻度组血清hs-CRP和DD水平显著高于正常妊娠组（P〈0.01）,而子痫前期重度组血清hs-CRP和DD水平显著高于轻度组（P〈0.01）。结论：子痫前期患者血清hs-CRP和DD水平增高,二者可以作为诊断及判定病情严重程度的敏感指标。

Clinical significance of high-sensitivity C-reactive protein and D-dimer detection in patients with preeclampsia

Objective： To explore the clinical value of high-sensitivity C-reactive protein （hs-CRP） and D-dimer （DD） detection in patients with preeclampsia. Methods： 62 cases preeclampsia pregnant women （34 cases of mild and 28 cases of severe illness） were selected, chose normal pregnant women in late pregnancy in 35 cases, and chose 32 females physical health of non-pregnant （control group）. The high-sensitivity C-reactive protein and D-dimer of all selected objects were detected. Results： The level of high-sensitivity C-reactive protein and D-dimer in preeclampsia patients and normal pregnant women were significantly higher than those of the control group （P〈0.01）. The level of high-sensitivity C-reactive protein and D-dimer in preeclampsia patients were higher than those of the normal pregnant women （P〈0.01）. The level of high-sensitivity C-reactive protein and D-dimer in severe preeclampsia patients were higher than those of mild preeclampsia patients （P〈0.01）. Conclusion： The level of high-sensitivity C-reactive protein and D-dimer in preeclampsia patients increase obviously, which can be used to diagnose preeclampsia and evaluate the severity of condition as sensitive indicators.