20例新生儿医院感染肺炎克雷伯菌败血症临床研究

目的：探讨新生儿医院感染肺炎克雷伯菌败血症临床特征和疗效。方法：回顾统计分析2009～2010年20例新生儿医院感染肺炎克雷伯菌败血症患儿的临床特征,以及患儿的药敏反应资料和治疗效果。结果：通过治疗,20例患儿中18例治愈,1例好转转入其他医院进一步治疗,1例无效死亡。药敏反应中,青霉素和头孢类几乎全部耐药,而含酶抑制剂类、氨基糖苷类和喹诺酮类抗生素敏感率较高。结论：美洛培南和亚胺培南为治疗克雷伯菌败血症的首选用药。

Clinical research of 20 cases with neonatal Klebsiella sepsis in hospital-acquired pneumonia

Objective： To evaluate neonatal Klebsiella sepsis in hospital-acquired pneumonia clinical features and effica- cy. Methods： Statistical analyzed from 2009 to 2010 years 20 cases of neonatal nosocomial Klebsiella pneumoniae infec- tion in children with clinical features of sepsis, as well as information on children＇s susceptibility and response to treat- ment. Results： Through treatment, 18 cases were cured among 20 patients, 1 case improved transferred to other hospitals for further treatment, 1 case died. Sensitivity reaction, penicillin and cephalosporins resistant to almost all, and with enzyme inhibitors, aminoglycosides and quinolones sensitivity was higher. Conclusion： Meropenem and imipenem for the treatment of Klebsiella sepsis drug of choice.