| 喹硫平对精神分裂症患者血脂代谢的影响 |
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| 引用本文： | 顾引军,张其荣,庄开岺,罗文秀,陈俊,王祖承,粟幼嵩. 喹硫平对精神分裂症患者血脂代谢的影响[J]. 中国医药指南, 2011, 9(21): 177-177,180 |
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| 作者姓名： | 顾引军 张其荣 庄开岺 罗文秀 陈俊 王祖承 粟幼嵩 |
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| 作者单位： | 1. 上海市金山区精神卫生中心,上海,201502
2. 上海交通大学医学院附属精神卫生中心,上海,200025 |
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| 基金项目： | 上海交通大学医学院自然科学基金 |
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| 摘 要： | 目的探讨喹硫平对精神分裂症患者血脂代谢的影响,并比较男女之间的差异。方法 2006年1月至2009年1月期间入院予喹硫平治疗的精神分裂症患者346例,分析喹硫平治疗8周前后的空腹血胆固醇(TC)、三酰甘油(TG)浓度变化。结果喹硫平治疗组TC及TG前后变化不明显,差异均无统计学意义(t=1.45),且男女患者之间无明显差异(t=1.03,P>0.05)。结论喹硫平对精神分裂症患者血脂代谢的影响不大,对于高血脂患者用药安全。
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| 关 键 词： | 喹硫平 精神分裂症 血脂 |
Effects of Quetiapine on Sermn lipids Metabolism in Schizophrenic Patients. |
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| GU Yin-Jun,ZHANG Qi-rong,ZHUANG Kai-Ling,LUO Wen-Xiu,CHEN-Jun,WANG Zu-cheng,SU You-song. Effects of Quetiapine on Sermn lipids Metabolism in Schizophrenic Patients.[J]. Guide of China Medicine, 2011, 9(21): 177-177,180 |
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| Authors: | GU Yin-Jun ZHANG Qi-rong ZHUANG Kai-Ling LUO Wen-Xiu CHEN-Jun WANG Zu-cheng SU You-song |
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| Affiliation: | GU Yin-Jun1,ZHANG Qi-rong1,ZHUANG Kai-Ling1,LUO Wen-Xiu1,CHEN-Jun2,WANG Zu-cheng2,SU You-song2(1 Jinshan District Mental Health Center,Shanghai 201502,China,2 Shanghai Jiaotong University Mental Health Center,Shanghai 200025,China) |
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| Abstract: | Objective To explore the effects of quetiapine on sermn lipid metabolism in schizophrenic patients with their first episode.Method 346 schizophrenic patients were recruited who were admitted to A hospital from January 2006 to January 2009.To analysis the concentrations of TC and TG after 8 weeks quetiapine treatment.Results After quetiapine treatment,no significantly difference was found in TC and TG concentrations(t=1.37,P=0.14;t= 1.69,P=0.08),and no difference between sex(t=1.46,P=0.11;t=1.34,P=0.15).Conc... |
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| Keywords: | Quetiapine Schizophrenia Blood lipid |
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