| 某院578例药品不良反应报告分析 |
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| 引用本文： | 金剑,肖忠革,金芝贵,吴飞华. 某院578例药品不良反应报告分析[J]. 中国医药指南, 2011, 9(21): 178-180 |
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| 作者姓名： | 金剑 肖忠革 金芝贵 吴飞华 |
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| 作者单位： | 上海交通大学医学院附属第九人民医院药剂科,上海,200011 |
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| 摘 要： | 目的了解上海交通大学医学院附属第九人民医院药品不良反应(ADR)的发生情况及引发ADR的相关因素。方法对上海交通大学医学院附属第九人民医院2005年1月至2010年12月收集到的578例ADR进行回顾性统计与分析。结果 578例ADR报告中,女性多于男性,65岁以上老年患者占总例数的48.1%。给药方式中,静脉滴注引发的ADR最多,口服第二。涉及的药品种类中,抗感染药物居首位,其次是心血管药物,中药和解热镇痛药分别为第三、第四位。引起ADR的抗感染药中,喹诺酮类药物占首位,头孢菌素类药物居第二位,依次是林可霉素类、β-内酰胺酶抑制类。ADR的临床表现形式以过敏、消化系统反应比较多见。结论上海交通大学医学院附属第九人民医院ADR的发生以女性、老年患者居多,其临床表现多样,发生因素与患者年龄、给药途径、药品种类等相关。应加强对ADR的监测及相关知识的宣传,以减少和避免ADR的发生。
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| 关 键 词： | 药品不良反应 监测 |
Analysis on 578 Adverse Drug Reaction Case Reports |
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| JIN Jian,XIAO Zhong-ge,JIN Zhi-gui,WU Fei-hua. Analysis on 578 Adverse Drug Reaction Case Reports[J]. Guide of China Medicine, 2011, 9(21): 178-180 |
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| Authors: | JIN Jian XIAO Zhong-ge JIN Zhi-gui WU Fei-hua |
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| Affiliation: | JIN Jian,XIAO Zhong-ge,JIN Zhi-gui,WU Fei-hua(Department of Pharmacy,Affiliated No.9th People's Hospital,Medical College of Shanghai Jiaotong University,Shanghai 200011,China) |
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| Abstract: | Objective To observe the occurrence of ADR in Affiliated No.9th People's Hospital,Medical College of Shanghai Jiaotong University and analyze its correlative factors.Methods:The 578 case reports of ADR collected from Jan 2005 to Dec 2010 in Affiliated No.9th People's Hospital,Medical College of Shanghai Jiaotong University and were analyzed statistically.Results Of the 578 patients,Females were more than males,There were 48.1%of patients who were older than 65.Most of them were resulted from iv which accoun... |
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| Keywords: | Adverse drug reactions Monitoring |
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