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轻中度高血压人群叶酸与同型半胱氨酸水平的相关分析
引用本文:汪国海,霍勇,王梦德,邢厚恂,刘平,臧桐华,徐希平. 轻中度高血压人群叶酸与同型半胱氨酸水平的相关分析[J]. 疾病控制杂志, 2007, 11(2): 171-173
作者姓名:汪国海  霍勇  王梦德  邢厚恂  刘平  臧桐华  徐希平
作者单位:1. 安徽医科大学生物医学研究所,安徽,合肥,230032
2. 北京大学第一医院心内科,北京,100034
摘    要:目的探讨轻中度高血压患者血清叶酸水平与血浆总同型半胱氨酸水平(tHcy)的相关性。方法从哈尔滨、沈阳、北京、西安、上海和南京六城市分析455位28~75岁轻中度原发性高血压患者,测定血清叶酸和血浆同型半胱氨酸水平。结果叶酸水平低于15nmol/L时,叶酸水平越低,tHcy水平越高,高tHcy血症的发生率也越高。结论轻中度高血压患者中,血清叶酸水平与血浆tHcy水平呈负相关。

关 键 词:叶酸  半胱氨酸  高血压
文章编号:1008-6013(2007)02-0171-03
收稿时间:2006-12-10
修稿时间:2007-02-28

Association of serum folic acid concentration and plasma total homocysteine concentration in population with mild-moderate hypertension
WANG Guo-hai,HUO Yong,WANG Meng-de,XING Hou-xun,LIU Ping,ZANG Tong-hua,XU Xi-ping. Association of serum folic acid concentration and plasma total homocysteine concentration in population with mild-moderate hypertension[J]. Chinese Journal of Disease Control and Prevention, 2007, 11(2): 171-173
Authors:WANG Guo-hai  HUO Yong  WANG Meng-de  XING Hou-xun  LIU Ping  ZANG Tong-hua  XU Xi-ping
Affiliation:WANG Guo-hai, HUO Yong, WANG Meng-de, XING Hou-xun, LIU Ping , ZANG Tong-hua, XU Xi-ping(1. Biomedical Institute, Anhui Medical University, Hefei 230032, China ; 2. Department of Cardiology, The First Hospital of Peking University, Beijing 100034, China)
Abstract:Objective To analyze the relationship between serum folic acid level and plasma total homocysteine (tHcy) level on mild-moderate hypertension, Methods 455 (aged 28-75) essential hypertensive patients from Harbin, Shenyang, Beijing, Xi'an, Shanghai and Nanjing were analysed. Serum folic acid level and plasma total homocysteine levels were measured, Results Serum folic acid levels were lower, plasma total homocysteine levels were higher, and hyperhomocysteinemia prevalence rate were also higher in population serum folic acid level under 15 nmol/L. Conclusions Relationship between serum folic acid level and plasma total homocysteine level is a negative correlation in population with hypertension.
Keywords:Folic acid   Cysteine   Hypertension
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