Abstract: | Three days after subdiaphragmal vagotomy, the rate of local blood flow in the muscular layer of rat jejunum increases, decreases on the 7th–30th day, and is normalized on the 60th–220th day. Po2 is lowered within 3–30 days, but not after 14 days. Microhemodynamic disturbances are accompanied by changes in the configuration of the microvessels, increased permeability of their walls, and modification of the aggregation status of the blood. Correlations between the dynamics of blood flow rate, its kinetic parameters, and Po2 on the one hand, and morphological reorganization of the microcirculatory bed, on the other, suggest that hypoxia of the small intestine muscles developing after vagotomy has a circulatory nature. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 126, No. 8, pp. 142–146, August, 1998. |