| 神经营养素与弱视发病机制的探讨 |
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| 引用本文： | 张荻,吴小影. 神经营养素与弱视发病机制的探讨[J]. 眼科研究, 2003, 21(6): 651-653 |
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| 作者姓名： | 张荻 吴小影 |
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| 作者单位： | 1. 湘雅医院眼科研究生
2. 410008,长沙,中南大学湘雅医学院 |
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| 摘 要： | 神经营养素是一群属于神经生长因子家族的分泌型蛋白质，可促进多种中枢和外周神经元的存活和分化，具有调控神经系统突触发育可塑性的效应，对神经系统的发育和成熟起重要作用。综述了神经营养素对视觉系统发育和可塑性变化的影响，及其在弱视的形成和转归中的作用，以期对弱视的治疗有所提示。
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| 关 键 词： | 神经营养素 弱视 视觉系统 可塑性 |
| 修稿时间： | 2002-12-03 |
Correlation of neurophins and the pathogenesis of amblyopia |
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| Zhang Di.Depart ment of Ophthalmology,Xiangya Hospital,Central South University,Changsha. Correlation of neurophins and the pathogenesis of amblyopia[J]. Chinese Ophthalmic Research, 2003, 21(6): 651-653 |
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| Authors: | Zhang Di.Depart ment of Ophthalmology Xiangya Hospital Central South University Changsha |
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| Affiliation: | Zhang Di.Depart ment of Ophthalmology,Xiangya Hospital,Central South University,Changsha 4 10008 |
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| Abstract: | It has been shown that neurotrophins,neurotrophic factors of nerve growth factor family,play an important role in activity-dependent develop ment and plasticity of the brain,in particular of the neocortex.They are import ant regulators of visual cortical plasticity.The potential effect of neurotrophi ns on the plasticity of the visual system and the role in the pathogenesis of am blyopia are discussed. |
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| Keywords: | neurotrophins amblyopia visual system plasticity |
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