| 不同生育期黄芩各部位活性成分动态变化 |
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| 引用本文： | 张琳,刘伟,王晓,段文娟,周洁,刘峰,张钦德. 不同生育期黄芩各部位活性成分动态变化[J]. 中国实验方剂学杂志, 2013, 19(19): 127-131 |
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| 作者姓名： | 张琳 刘伟 王晓 段文娟 周洁 刘峰 张钦德 |
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| 作者单位： | 山东中医药大学药学院, 济南 250355;山东省科学院中药过程控制研究中心/山东省分析测试中心, 济南 250014;山东省科学院中药过程控制研究中心/山东省分析测试中心, 济南 250014;山东省科学院中药过程控制研究中心/山东省分析测试中心, 济南 250014;山东省科学院中药过程控制研究中心/山东省分析测试中心, 济南 250014;山东省科学院中药过程控制研究中心/山东省分析测试中心, 济南 250014;山东省科学院中药过程控制研究中心/山东省分析测试中心, 济南 250014;山东中医药高等专科学校, 山东 烟台 264199 |
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| 摘 要： | 目的: 研究不同生育期山东产黄芩各部位活性成分含量的变化。方法: 采用HPLC测定山东莱芜和平阴两地2年生黄芩不同生育期地上和地下部分活性成分的含量。结果: 两地黄芩地上部位的野黄芩苷含量最高,分别为15.46,11.83 mg·g-1。地下部分,莱芜黄芩所含黄芩苷和汉黄芩苷在整个生育期呈下降趋势,最高含量在展叶期,分别为173.60,34.31 mg·g-1,平阴黄芩所含黄芩苷和汉黄芩苷则出现2个最高含量,分别为176.40,212.94 mg·g-1和28.93,34.21 mg·g-1。两地黄芩的黄芩素和汉黄芩素含量分别有2个高峰期,莱芜黄芩所含黄芩素在始花期和采收期达到高峰,分别为8.05,9.49 mg·g-1;汉黄芩素含量分别在始花期和采收期达到高峰,分别为1.94,3.75 mg·g-1。平阴黄芩所含黄芩素和汉黄芩素在展叶期和成熟期达到高峰,分别是12.80,8.27 mg·g-1和2.70,1.48 mg·g-1。结论: 野黄芩苷以地上部位较高,而黄芩苷则以地下部位为高;地下部的黄芩苷和汉黄芩苷含量(从展叶期到采收期)基本呈"M"型变化趋势,黄芩素和汉黄芩素基本呈倒"N"型变化趋势。
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| 关 键 词： | 黄芩 生育期 不同部位 活性成分 含量 |
| 收稿时间： | 2013-03-06 |
Dynamic Changes of Active Constituents in Different Growth Stage of Scutellaria baicalensis |
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| ZHANG Lin,LIU Wei,WANG Xiao,DUAN Wen-juan,ZHOU Jie,LIU Feng and ZHANG Qin-de. Dynamic Changes of Active Constituents in Different Growth Stage of Scutellaria baicalensis[J]. China Journal of Experimental Traditional Medical Formulae, 2013, 19(19): 127-131 |
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| Authors: | ZHANG Lin LIU Wei WANG Xiao DUAN Wen-juan ZHOU Jie LIU Feng ZHANG Qin-de |
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| Affiliation: | Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China;Process Control Research Center of TCM, SDAS/Shandong Analysis and Test Center, Ji'nan 250014, China;Process Control Research Center of TCM, SDAS/Shandong Analysis and Test Center, Ji'nan 250014, China;Process Control Research Center of TCM, SDAS/Shandong Analysis and Test Center, Ji'nan 250014, China;Process Control Research Center of TCM, SDAS/Shandong Analysis and Test Center, Ji'nan 250014, China;Process Control Research Center of TCM, SDAS/Shandong Analysis and Test Center, Ji'nan 250014, China;Process Control Research Center of TCM, SDAS/Shandong Analysis and Test Center, Ji'nan 250014, China;Shangdong College of Traditional Chinese Medicine, Yantai 264199, China |
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| Abstract: | Objective: To investigate the changes of active composition in different parts and growth stages of Scutellaria baicalensis in Shandong Province. Method: HPLC technology was employed to detect the content of active composition in two-years old plant samples which collected from Laiwu and Pingyin in five different growth stages. Result: The content of scutellarin got to the highest value of 15.46,11.83 mg·g-1 in the part of aboveground in the beginning of flowering stage and leaf-expansion stage, respectively. The content of baicalin and wogonoside in the root which collected from Laiwu decreased in the whole growth stage, the content was 173.60,34.31 mg·g-1respectively, while the content in the samples collected from Pinyin was 176.40, 212.94 mg·g-1in flower stage and 28.93, 34.21 mg·g-1 in mature stage respectively. The content of baicalein in the sample of Laiwu was 8.05,9.49 mg·g-1in the beginning of flowering stage and maturity stage respectively. The content of wogonin was 1.94,3.75 mg·g-1 in the beginning of flowering stage and withering stage respectively, while the content was 12.80, 8.27 mg·g-1and 2.70, 1.48 mg·g-1 in leaf-expansion and withering stage in the samples collected from Pingyin. Conclusion: The content of scutellarin in aboveground is higher than that in underground which opposite to the content of baicalin; the content of baicalin and wogonoside from leaf-expansion to withering stage shows a trend of M style, while the content of baicalein and wogonin shows a trend of N style. |
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| Keywords: | Scutellaria baicalensis growth stage different parts active composition content |
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