高温高湿环境运动后人生命体征及脑血流的变化

目的 研究高温高湿环境运动后人生命体征和脑血流的改变情况以及药物乌拉地尔降低脑温的效果。方法 90名战士，分成新战士组、新战士服药组(运动前7h和3h口服盐酸乌拉地尔各30mg)及老战士组(下简称A、B、C组)，测定常温静息状态下及高温高湿环境下20rnin内跑步3000m后的体温、脉搏、血压及脑血流情况。结果 常温静息状态下，3组体温、脉搏、血压及脑血流差异无显著性意义。高温高湿环境下运动后，体温、脉搏、收缩压及脑血流速度较运动前均有明显升高，舒张压有所下降，脉动指数(PI)无明显改变；运动后B组体温低于A组，C组脑血流速度高于、脉动指数低于A组。结论 高温高湿环境运动后人生命体征及脑血流变化显著；老战士较新战士具有更好的热适应能力；乌拉地尔具有药物降脑温的作用。

Changes of vital signs and cerebral blood flow after sport in hyperthermal and heavy humid environment

Objective To investigate the changes of vital signs and cerebral blood flow after sport in hyperthermal and heavy humid environment; and to investigate the effect of Urapidil on these changes. Methods 90 soldiers were divided into three groups: new soldiers group, new soldiers taking Urapidil group and veterans group(as group A,B,C). Their vital signs and cerebral blood flow were measured at quiescent condition in normal temperature and after their running for 3000m within 20 minutes in hyperthermal and heavy humid environment. Results Little difference was found among the three groups at guiescent condition in normal temperature. Whereas after exercise, there was significant elevation in body temperature, pulse, systolic pressure and cerebral blood velocity. On the other hand, a little decline in diastolic pressure was showed, but no obvious changes in pulsatility index(PI) following the exercise. Compared with group A, the average body temperature in group B was lower. The cerebral blood velocity in group C was faster and the PI showed lower. Conclusion Sport in hyperthermal and heavy humid environment could significantly affect vital signs and cerebral blood flow of human. The veterans had acquired better heat adaptation than the new soldiers. Urapidil played an important role in pharmacological hypothermia.