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溶脲脲原体感染导致大鼠泌尿道形成结石
引用本文:王勇,韩晓冬,侯亚义.溶脲脲原体感染导致大鼠泌尿道形成结石[J].医学研究生学报,2004,17(2):120-121.
作者姓名:王勇  韩晓冬  侯亚义
作者单位:南京大学医学院,江苏南京,210093
基金项目:南京大学“985”工程基金,“高等学校骨干教师资助计划”资助项目
摘    要:目的:研究溶脲脲原体(ureaplasma urealyticum,UU)感染对雄性大鼠泌尿生殖系统结石形成的影响,从而探究引起雄性大鼠泌尿生殖道结石形成的途径与机制。方法:采用模拟性交的自然方式使雄性SD大鼠反复感染UU。8周末处死大鼠,解剖泌尿生殖系统,观察有无异常。结果:12.5%的大鼠尿道口及尿道中有白色略呈半透明的块状固体,质软,为软结石;27.5%的大鼠膀胱中有结石,其中12.5%为软结石,15%为硬结石,结石的数目不等,少的数枚,多的十多枚;肾盂、曲细精管中未发现结石。结论:UU感染可导致大鼠泌尿道形成结石。

关 键 词:溶脲脲原体  结石  大鼠
文章编号:1008-8199(2004)02-0120-02
修稿时间:2003年9月13日

Ureaplasma urealyticum infection induced the production of calculus in urinary and reproductive system of male rats
WANG Yong,HAN Xiao-dong,HOU Ya-yi.Ureaplasma urealyticum infection induced the production of calculus in urinary and reproductive system of male rats[J].Bulletin of Medical Postgraduate,2004,17(2):120-121.
Authors:WANG Yong  HAN Xiao-dong  HOU Ya-yi
Abstract:Objective:To investigate affection of ureaplasma urealyticum (UU) infection on the production of calculus of the urinary and reproductive system in male rat. Methods:Sprogue-dawley(SD) rats were infected with UU4 (serotype 4) through repeated natural sexual intercourses for 8 weeks. The urinary and reproductive system were detected . Results:Twelve point five percents of rate infected with UU had soft calculus in urinary tracts, while 27.5 percents of rate infected with UU had soft or hard calculus. Conclusion: Infection with UU may lead to the production of calculus in urinary and reproductive system in male rats
Keywords:Ureaplasma urealyticum  Calculus  Male rat
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