100例低清蛋白血症患者血流变学检测结果分析

目的：低清蛋白血症是引起住院患者出现并发症和死亡的主要原因。本研究探讨血液流变学指标的变化与低清蛋白血症患者的相互关系,了解血液流变学指标的变化在低清蛋白血症中的预警作用。方法：对100例住院低清蛋白血症老年患者进行血液流变学检查并分析结果。结果：住院患者的血流变学检测结果显示,患者全血粘度高切、全血粘度中切（100/s）、全血粘度中切（30/s）、全血粘度低切、血浆粘度、血沉、血沉方程K值、全血还原粘度高切、红细胞聚集指数、红细胞刚性指数、红细胞电泳时间、全血还原粘度低切均有显著差异（P〈0.05）。患者红细胞压积男性有明显差异（P〈0.05）,女性无明显差异（P〉0.05）。结论：老年人因其生理、病理特点较易发生低蛋白血症,继而并发低粘滞综合征,且发病隐蔽,表现不典型,容易漏诊,故要仔细观察病情,一旦发现血清白蛋白下降要及时给予综合治疗。常规检查住院病人的血液流变学指标,对低清蛋白血症发生有早期预警作用。

Analysis of blood rheology in 100 patients with hypoalbuminemia

Objective：To investigate the changes of hemorheological indexes in patients with hypoalbuminemia in relation to each other, to understand the change of Hemorheology in hypoalbuminemia in the early warning role. Hypoalbuminemia is the cause of inpatient complications and causes of death. Methods：We collected and analyzed data of blood rheology in 100 hospitalized elderly patients with hypoalbuminemia. Results： We found significant differences （ P 〈 0.05 ） in rheological measures between patients including whole blood viscosity at high and low shear rates, whole blood viscosity at medium shear rates of 30 and 100 per second, plasma viscos- ity, erythrocyte sedimentation rate （ESR）, K value of ESR, whole blood reductive viscosity at high and low shear rates, erythrocyte aggregation index, erythrocyte rigidity index, red cell electrophoretic time. The hematocrit level in male patients also differs significant- ly （P 〈 0.05 ） while in female patients there is no obvious variation （P 〉 0.05）. Conclusions： Hypoalbuminemia often develops in elderly people usually accompanied by blood hypoviscosity syndrome. Because of its atypical manifestation, extensive efforts and close examination are needed to diagnose. Routine examinations on blood rheology in hospitalized elderly patients should be employed as a precantious practice to diagnose hypoalbuminemia at early stage.