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Effect of sodium hypochlorite on the biotransformation of toxicants in acute poisoning by psychotropic agents |
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| Authors: | Petrov S I Belova M V Luzhnikov E A Gol'dfarb Iu S Il'iashenko K K Lisovik Zh A Baturova I V Popova M M El'kov A N |
| Abstract: | In acute poisoning by amitriptyline, carbazepine, barbiturates, and ethanol, the effect of sodium hypochlorite on the metabolism of toxicants is manifested as a considerable reduction in their high blood concentrations through oxidative transformation to inactive water-soluble derivatives and as the enhanced urinary elimination of the latter. The rate of the above process depends on the used dose of sodium hypochlorite. |
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