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Treatment of stiff-man syndrome with intravenous immune globulin
Authors:Elizabeth W Karlson  Lewis Sudarsky  Eric Ruderman  Susan Pierson  Mary Scott  Simon M Helfgott
Abstract:Objective. To evaluate the efficacy of intravenous immune globulin (IVIG) in the treatment of stiff-man syndrome (SMS). Methods. An open, unblinded study of 3 patients with active disease and/or disease refractory to treatment with diazepam and/or corticosteroids. Results. All 3 bedridden patients improved substantially shortly after infusion with IVIG and regained function. Conclusion. IVIG may be useful for the treatment of SMS.
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