IgE-dependent killing of Schistosoma mansoni schistosomula by human platelets: modulation by T cell products |
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| Authors: | V Pancré J Y Cesbron M Joseph M Barbier A Capron C Auriault |
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| Affiliation: | Centre d'Immunologie et de Biologie Parasitaire, Institut Pasteur, Lille, France. |
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| Abstract: | The in vitro stimulation of T lymphocytes is known to induce the release of factors that possess distinct biological activities. In the present report, we describe the presence, in supernatants of Schistosoma mansoni antigen stimulated T cells from S. mansoni infected patients, of a factor able to inhibit the IgE-dependent platelet cytotoxicity of the same individuals toward the young larvae of S. mansoni. |
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