OSAHS患者生存质量与社会支持等因素的相关性研究

目的 探讨OSAHS患者生存质量与社会支持、白天过度嗜睡(EDS)和多导睡眠图(PSG)指标等因素的关系,寻找影响OSAHS患者生存质量的因素.方法 连续纳入2007年8月至2007年11月在华西医院睡眠呼吸监测室行多导睡眠图(PSG)监测诊断为OSAHS的患者85例,分别采用Calgary生存质量指数(SAQLI)评价生存质量,社会支持评定量表(SSRS)评价接受到的社会支持情况.Epworth嗜睡量表(ESS)评价白天嗜睡程度.用Pearson直线相关和多元逐步回归方法分析SAQLI评分与上述因素的关系.结果 OSAHS患者SAQLI评分与SSRS评分呈正相关(r=0.402,P<0.01),与ESS评分呈负相关(r=-0.505,P<0.01),与睡眠呼吸暂停低通气指数(AHI)呈负相关(r=-0.269,P<0.05),与夜间最低动脉血氧饱和度(LSaO2)呈正相关(r=0.226,P<0.05).多元逐步回归分析最后仅纳入了SSRS和ESS评分作为SAQLI总分的独立预测变量,两者总共可以解释SAQLI总分变化的37.3%(R2=0.373,P<0.001).结论 OSAHS患者生存质量与社会支持、白天过度嗜睡和PSG指标密切相关,社会支持和白天过度嗜睡对OSAHS患者的生存质量的影响较大.

Relationships Between Health-Related Quality of Life and Social Support in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome

Objective To study the relationships among health-related quality of life(HRQL), social support, excessive daytime sleepiness (EDS) and PSG parameters in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS).Methods Eighty-five patients were recruited who were diagnosed as OSAHS by overnight po]ysomnography from August 2007 through November 2007 in West China Hospital.The Calgary sleep apnea quality of life index (SAQLI) was used for HRQL, social support rating scale (SSRS) was used for social support,and Epworth sleepiness scale(ESS) was used for EDS.The Pearson linear correlation and stepwise multiple regression analysis were used to analyze the correlation among SAQLI, SSRS, ESS, and PSG.Results The SAQLI was correlated with SSRS score (r = 0.402, P < 0.01) ; ESS score (r =-0.505 ,P <0.01) ; apnea-hypopnea index (AHI) (r =-0.269,P <0.05) and lowest artery oxygen saturation (ISaO2) (r = 0.226, P < 0.05).Stepwise muhiple regression analysis determined two variables,the SSRS and ESS score,as independent factors for predicting the total score of SAQLI which accounted for 37.3% of the total variance in the total score on SAQLI (R2 = 0.373, P < 0.001).Conclusions The HRQL of patients with OSAHS was correlated with the SSRS score, ESS score and PSG parameters.The former two were the more important factors to affect the HRQL of patients with OSAHS.