| 乌头汤的镇痛抗炎作用 |
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| 引用本文： | 毛理纳 洪素兰. 乌头汤的镇痛抗炎作用[J]. 河南医学研究, 1994, 3(4): 325-328 |
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| 作者姓名： | 毛理纳 洪素兰 |
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| 作者单位： | 河南省职工医学院药理室，河南中医学院，河南省医学科学研究所，商丘市人民医院 |
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| 基金项目： | 河南省中医管理局资助课题 |
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| 摘 要： | 乌头汤４０ｇ／ｋｇｉｇ与乌头汤１００％浓度浸足０．５ｈ均能显著提高小鼠对热刺激的痛阈；乌头汤２０ｇ／ｋｇｉｇ与４０ｇ／ｋｇｉｇ均可显著降低０．７％醋酸所致小鼠扭体反应发生率；同上剂量的乌头汤ｉｇ均可显著抑制二甲苯所致小鼠耳肿胀程度；乌头汤浸足０．５ｈ亦可显著抑制蛋清所致的大鼠足跖肿胀；每天大鼠ｉｇ１００％浓度乌头汤，１５ｇ／ｋｇ，连续给药７天，有显著抑制大鼠棉球肉芽肿作用。
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| 关 键 词： | 乌头汤，镇痛作用，抗炎作用 |
ANALGESIC AND ANTI-INFLAMMATORY EFFECT OF DECOCTION OF ACONITUM CARMICHAELI |
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| Mao Li-na Hong Su-lan Luo Yu et al. ANALGESIC AND ANTI-INFLAMMATORY EFFECT OF DECOCTION OF ACONITUM CARMICHAELI[J]. Henan Medical Research, 1994, 3(4): 325-328 |
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| Authors: | Mao Li-na Hong Su-lan Luo Yu et al |
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| Abstract: | Decoction of Aconitum carmichaeli Debx(ACD).ACD ig 40g/kg can raise thepain threshold of thermal stimulation in mice.Decoction of ACD 20g/kg or 40g/kg markedlyinhibited the rateof body twisting reaction induced by ip 0.7%acetic acid in mice and it alsoinhibited the swelling of mouse ear induced by xylene.Decoction of ACD bathing feet for 30minutes can significantly inhibit the swelling of hind paw induced by sc fresh egg white 0.1ml in rats. Daily ig Decoction of ACD at the dose of 15g/kg for 7 days can markedly inhibitthe formation of granuloma induced by cotton pellets in rats. |
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| Keywords: | Decoction of Aconitum carmichaeli Debx analgesic effect anti-inflammatoryeffect |
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