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| 赤式氨基苯基丙醇合成工艺改进 | |
| 引用本文： | 蔡小华,胡薇,姚祖凤. 赤式氨基苯基丙醇合成工艺改进[J]. 中国药物化学杂志, 2002, 12(2): 110-111 |
| 作者姓名： | 蔡小华 胡薇 姚祖凤 |
| 作者单位： | 1. 怀化医学高等专科学校药学系,湖南,怀化,418000 2. 南晶机电化工研究所,江西,南昌,330047 3. 湖南吉首大学生命科学与化学学院,湖南,吉首,416000 |
| 摘 要： | 以苯丙酮为起始原料，经过羟亚氨基苯丙酮中间体和用Pt－Pd/C作催化剂加氢反应合成赤式－2－氨基－1－苯基－丙酮，并对其工艺进行了改进，降低了成本，简化了工艺，提高了收率，总收率55．5％。 |
| 关 键 词： | 苯丙酮 羟亚氨基苯丙酮 赤式－2－氨基－1－苯基－1－丙酮 合成 |
| 文章编号： | 1005-0108(2002)02-0000-02 |
Study on the synthesis of erythro-2-amino-1-phenyl-1-propanol |
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| CAI Xiao hua ,HU Wei+,YAO Zu feng+. Study on the synthesis of erythro-2-amino-1-phenyl-1-propanol[J]. Chinese Journal of Medicinal Chemistry, 2002, 12(2): 110-111 | |
| Authors: | CAI Xiao hua HU Wei+ YAO Zu feng+ |
| Affiliation: | CAI Xiao hua 1,HU Wei+2,YAO Zu feng+3 |
| Abstract: | The synthetic method of erythro 2 amino phenyl 1 propanol was reported.It was started from propiophenone via the intermediate oximinopropiophenone and catalytic hydrogention.Some improvements were made,the cost was low,the processing was simple and the yield was increased.Its total yield was 55 5%. |
| Keywords: | propiophenone oximinopropiophenone erythro 2 amino phenyl 1 propanol synthesis |
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