Comparison of Roche MONITOR and Organon Teknika NucliSens assays to quantify human immunodeficiency virus type 1 RNA in cerebrospinal fluid |
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| Authors: | Spearman P Fiscus S A Smith R M Shepard R Johnson B Nicotera J Harris V L Clough L A McKinsey J Haas D W |
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| Affiliation: | Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. paul.spearman@mcmail.vanderbilt.edu |
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| Abstract: | We compared Roche MONITOR and Organon Teknika NucliSens assays for human immunodeficiency virus type 1 (HIV-1) RNA in cerebrospinal fluid (CSF). Results of 282 assays were highly correlated (r = 0.826), with MONITOR values being 0.29 +/- 0.4 log(10) copies/ml (mean +/- standard deviation) values. Both assays can reliably quantify HIV-1 RNA in CSF. |
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