帕罗西汀辅助治疗功能性消化不良

目的:观察帕罗西汀佐治功能性消化不良(FD)的临床效果. 方法:将70例FD随机分为两组,对照组(34例)予多潘立酮10 mg每日3次口服,奥美拉唑20 mg每日2次口服;治疗组(36例)在对照组治疗的基础上加用帕罗西汀10～20 mg,每日1次口服.两组疗程均为4周,观察两组效果. 结果:治疗组近期临床治愈21例,显效10例,有效3例,无效2例,近期临床治愈率为58.3%,总有效率为94.4%;对照组近期临床治愈8例,显效8例,有效10例,无效8例,近期临床治愈率为23.5%,总有效率为76.5%.两组近期临床治愈率比较差异有统计学意义(P＜0.01),总有效率比较差异亦有统计学意义(P＜0.05). 结论:在FD常规治疗基础上,联合帕罗西汀抗抑郁治疗,可起到协同作用,对FD有良好的疗效.

Paroxetine in the Treatment of Functional Dyspepsi

Objective:To observe the clinical effect of treating functional dyspepsia with Paroxetine.Methods:70 FD patients were randomly divided into 2 groups:the treatment group(n=36) and the control group(n=34).The patients in the control group were given 10 mg of Domperidone t.i.d.and 20 mg of Prilosec twice a day orally and the patients in the treatment group were given the same medication as the control group plus 10-20 mg of Paroxetine once a day in a 4-week period of treatment.The effects between the two group...