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Long‐term follow‐up of 2 patients treated with 90Y‐rituximab radioimmunotherapy for relapse of nodular lymphocyte‐predominant Hodgkin lymphoma
Authors:Sophie C. Golstein  Kristoff Muylle  Marie Vercruyssen  Chloé Spilleboudt  Alexandre de Wind  Dominique Bron
Affiliation:1. Department of Hematology, Institut Jules Bordet (ULB), Brussels, Belgium;2. Department of Nuclear Medicine, Institut Jules Bordet (ULB), Brussels, Belgium;3. Department of Pathological Anatomy, Institut Jules Bordet (ULB), Brussels, Belgium
Abstract:Nodular lymphocyte‐predominant Hodgkin lymphoma (NLPHL) is a rare lymphoma (<5% of Hodgkin’s lymphomas) predominantly affecting the middle‐aged man, with an indolent behavior. Given the rare occurrence of this lymphoma, there are currently no clear guidelines for initial treatment or relapse. In this report, we present the follow‐up of 2 patients treated by radioimmunotherapy for first relapse of their NLPHL. Both patients were initially treated with rituximab and relapsed 1 year after the end of their treatment.
Keywords:90Y‐rituximab  nodular lymphocyte‐predominant Hodgkin lymphoma  radioimmunotherapy  salvage treatment
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