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抗心律失常药物应用和安全性评价进展
引用本文:庄晓华,陈韬,徐涛,廖德宁.抗心律失常药物应用和安全性评价进展[J].药学服务与研究,2012,12(6):454-457.
作者姓名:庄晓华  陈韬  徐涛  廖德宁
作者单位:1. 上海市浦东医院心血管内科,上海,201399
2. 解放军空军航空大学门诊部,长春,130000
3. 第二军医大学长征医院心血管内科,上海,200003
摘    要:抗心律失常药有治疗心律失常的作用,同时有致心律失常作用。临床上在应用各种抗心律失常药时,除了考虑充分利用其抗心律失常作用外,还应全面关注其安全性。本文通过对抗心律失常药物的作用机制以及对心律失常发生、维持机制的分析,对抗心律失常药物的应用和安全性评价进展作一综述。

关 键 词:抗心律失常药  心律失常  药物副反应报告系统  综述

Advances in applications of anti-arrhythmia agents and safety evaluation
ZHUANG XiaoHua , CHEN Tao , XU Tao , LIAO DeNing.Advances in applications of anti-arrhythmia agents and safety evaluation[J].Pharmaceutical Care and Research,2012,12(6):454-457.
Authors:ZHUANG XiaoHua  CHEN Tao  XU Tao  LIAO DeNing
Institution:1.Department of Cardiovasology,Shanghai Pudong Hospital,Shanghai 201399,China;2.Department of Outpatient,Air Force Aeronautical Engineering University of PLA,Changchun 130000,China;3.Department of Cardiovasology,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China)
Abstract:Anti-arrhythmia agents have the therapeutic effect of anti-arrhythmia and could result in arrhythmia as well.When anti-arrhythmia drugs were applied clinically,considerations should not be given only to their anti-arrhythmia effect,but also to their overall safety.This paper is a comprehensive review directed at the applications of anti-arrhythmia drugs and safety evaluations,through analyses of the mechanism of anti-arrhythmia drugs,the occurrence and maintenance of arrhythmia involved.
Keywords:anti-arrhythmia agents  arrhythmia  adverse drug reactions reporting system  review
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