Stimulatory effect of an LHRH-agonist on testicular blood flow in hypophysectomized rats |
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| Authors: | J.-E. Damber A. Bergh L. Daehlin |
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| Affiliation: | Departments of Clinical Chemistry Physiology, University of Umeå, Umeå, Sweden;Departments of Pathology, Anatomy, University of Umeå, Umeå, Sweden;Departments of Urology and Andrology, University of Umeå, Umeå, Sweden |
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| Abstract: | The effect of an LHRH-agonist (A) on testicular blood flow and plasma testosterone levels was studied in adult hypophysectomized rats. Subcutaneous injection of 1 microgram LHRH-agonist 2 or 4 h prior to experiment induced an increase in testicular blood flow. (Controls: 21.1 +/- 2.8 ml/100 g X min; LHRH-A + 2 h: 28.9 +/- 3.3 ml/100 g X min; LHRH-A + 4 h: 32.4 +/- 4.1 ml/100 g X min P less than 0.05; all mean +/- SEM). There was also a significant increase in plasma testosterone levels at 2 h (P less than 0.01) and 4 h (P less than 0.01) after treatment with the LHRH-agonist, with a peak at 2 h. |
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| Keywords: | LHRH-agonist testicular blood flow testosterone hypophysectomized rats |
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