Cytotoxic ent-kaurane diterpenoids from Isodon weisiensis C. Y. Wu |
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Authors: | Ding Lan Liu Guo-Ah Yang Dong-Juan Wang Han Wang Lai Sun Kun |
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Affiliation: | College of Life Science, Northwest Normal University, Lanzhou, PR China. dinglan641@sina.com |
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Abstract: | A new ent-kaurane diterpenoid, weisiensin B (1), was isolated from the leaves of Isodon weisiensis C. Y. Wu, along with four known ones, kamebanin (2), kamebacetal A (3), macrocalyxin D (4) and excisanin D (5). Their structures were determined by spectroscopic means. Compound 1-4 showed significant cytotoxic activity against Bel-7402 and HO-8910 cells. |
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