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Cytotoxic ent-kaurane diterpenoids from Isodon weisiensis C. Y. Wu
Authors:Ding Lan  Liu Guo-Ah  Yang Dong-Juan  Wang Han  Wang Lai  Sun Kun
Affiliation:College of Life Science, Northwest Normal University, Lanzhou, PR China. dinglan641@sina.com
Abstract:A new ent-kaurane diterpenoid, weisiensin B (1), was isolated from the leaves of Isodon weisiensis C. Y. Wu, along with four known ones, kamebanin (2), kamebacetal A (3), macrocalyxin D (4) and excisanin D (5). Their structures were determined by spectroscopic means. Compound 1-4 showed significant cytotoxic activity against Bel-7402 and HO-8910 cells.
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