| 中国人参茎叶皂甙对大鼠行为的影响 |
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| 引用本文： | 曹颖林,戚靖安.中国人参茎叶皂甙对大鼠行为的影响[J].沈阳药科大学学报,1996,13(3):185-188,206. |
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| 作者姓名： | 曹颖林 戚靖安 |
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| 作者单位： | [1]沈阳药科大学药学系 [2]本溪钢铁公司职工总医院 |
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| 摘 要： | 人参茎叶皂甙５０ｍｇ／ｋｇ灌胃给大白鼠，每天１次，连续７天，于末次给药后１ｈ，采用主动回避反应；被动回避反应；分辨学习等训练方法对受试物进行研究，结果表明人参茎叶皂甙对正常大鼠学习、记忆过程仅有微弱易化作用。通过探索行为研究表明，人参茎叶皂甙明显增加每个训练日大白鼠第１分钟探索活动次数并加速探索活动的适应。对电休克大鼠短期记忆障碍有明显改善作用。
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| 关 键 词： | 人参茎叶皂甙 主动回避反应 被动回避反应 空间分辨学习 电休克 探索活动 |
EFFECTS OF CHINESE GINSENG STEM-LEAF SAPONINS OF BEHAVIOR OF RATS |
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| Cao Yinglin,V,D,petcov,I.K Todovov.EFFECTS OF CHINESE GINSENG STEM-LEAF SAPONINS OF BEHAVIOR OF RATS[J].Journal of Shenyang Pharmaceutical University,1996,13(3):185-188,206. |
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| Authors: | Cao Yinglin V D petcov IK Todovov |
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| Abstract: | Chinese ginseng stem-leaf saponins had slightly more effects on normal rats pretreated with it for 7 Days than on the controls in shuttle-box and step-down tests but increased the number of both horizontal and vertical movements in the first minute after a course of four consecutive Days in contrast to the controls,and promoted habituation of animals to unfamiliar enviroment.Ginseng Stem-Leaf saponing showed a memory facilitating effect on the animals with impaired memory due to electrocunvulsive shock in stem-down tests. |
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| Keywords: | Ginseng Stem-Leaf saponing Active avoidance Passive avoidance Spatial discrimimation learning Electrocunvulsive shock Exploratory behavior |
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